Radiofrequency Catheter Ablation for Atrial Fibrillation Followed by Cardiac Resynchronization Therapy in a Case of Lamin-Related Cardiomyopathy: A Case Report

Pulmonary vein isolation treats symptomatic AF in a patient with Lamin A/C mutation: case report and review of the literature

“…Treatment options were intensively discussed with the patient and she was informed that little evidence regarding the outcome of PVI in patients with laminopathy is existent. The latest ESC and HRS guidelines on AF do not comment on treatment of this specific patient collective [ 14 , 15 ] and by an intensive literature review only one case of successful radiofrequency (RF) ablation in a patient with laminopathy was found [ 16 ]. Despite low evidence, due to severe symptomatic AF episodes and only mild atrial dilatation (42 mm diameter in TTE), the individual treatment decision was made: In April 2018 the patient received cryoballoon PVI using the second generation cryoballoon (Medtronic, Dublin, Ireland) in typical anatomical configuration with two left- and two right-sided pulmonary veins and standard setting with an esophageal thermo probe (Fig.…”