2008
DOI: 10.1159/000184736
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Abstract: Background: A recent proposal of a randomized trial comparing resection and radiofrequency ablation (RFA) in a selected subgroup of patients with small resectable colorectal liver metastases (CRLM) has initiated a debate on this issue. Meanwhile, new data have been published. The aim of the study was to update and critically review the oncological evidence in favor of and against the use of RFA for resectable CRLM in general and in favor of and against conducting a randomized trial in a selected subgroup of pa… Show more

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Cited by 155 publications
(124 citation statements)
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“…The data in the literature is scant. 1,2,3,[8][9][10][11] Our group offers a multimodality treatment to patients with colorectal liver metastasis with adjunctive laparoscopic RFA and resection programs. In the present study, our aim was to compare the clinical and oncological profiles and survival of patients with solitary liver metastasis who were channeled to RFA versus liver resection at a single institution.…”
Section: Introductionmentioning
confidence: 99%
“…The data in the literature is scant. 1,2,3,[8][9][10][11] Our group offers a multimodality treatment to patients with colorectal liver metastasis with adjunctive laparoscopic RFA and resection programs. In the present study, our aim was to compare the clinical and oncological profiles and survival of patients with solitary liver metastasis who were channeled to RFA versus liver resection at a single institution.…”
Section: Introductionmentioning
confidence: 99%
“…The ultimate goal of MILS is to minimize tissue damage, surgical trauma, and immunosuppression in order to improve postoperative outcome in both the short-and long-term. Although several studies support the beneficial impact of MILS on the shortterm outcome after surgery for CRLM, data with respect to the long-term oncologic outcome are far from sufficient [9][10][11][12][13]. On the other hand, no data are available that assess prognostic factors in the era of current modern treatment strategies that combine systemic anticancer therapies and minimally invasive surgery.…”
mentioning
confidence: 99%
“…Aufgrund der forbestehenden, durch die Leberzirrhose bedingten Präkanzerose kommt es bei bis zu 50% der Patienten zu einem Wiederauftreten des HCC nach 3 Jahren [60]. Aktuelle Metaanalysen zeigen ferner für kleinere Tumoren bis 3 cm Durchmesser, dass die Ergebnisse nach RFTA denen der resezierenden Chirurgie gleichwertig sind [69]. [98].…”
Section: Abb 4 9 79-jähriger Patient Mit Einem Riesigen Hcc In Der Lunclassified