Radical Scavenging Activities of Heracleum aquilegifolium Wight (Apiaceae) Fruit Oils in vitro

Abstract

The fruits of Heracleum aquilegifolium Wight (Apiaceae) were collected from Western Ghats of the Indian Peninsula. The essential oils were extracted by hydrodistillation. The chemical composition of the essential oils was analysed by gas chromatography and gas chromatography-mass spectrometry (GC-MS). -Pinene (22.3%), 1,8-cineole (20.3%), and -phellandrene (12.4%) were the main components of H. aquilegifolium fruit oils. The antioxidant properties of essential oils of H. aquilegifolium were examined by different procedures namely reducing power ability, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, nitric oxide radical scavenging activity, hydrogen peroxide scavenging activity, hydroxyl radical scavenging activity, superoxide anion scavenging activity, and metal chelating activity. The antioxidant activities were compared with those of synthetic antioxidants and standard drugs such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), ascorbic acid, -tocopherol, curcumin, and quercetin. The study confi rmed the possible antioxidant potential of essential oils tested with various in vitro antioxidant methods. The presence of monoterpenes in combination with other components in the oils could be responsible for the activity.

Chemoprevention Against Arsenic-Induced Mutagenic DNA Breakage and Apoptotic Liver Damage in Rat Via Antioxidant and SOD1 Upregulation by Green Tea (Camellia sinensis) which Recovers Broken DNA Resulted from Arsenic-H2O2Related in Vitro Oxidant Stress

“…This Downloaded by [Temple University Libraries] at 20:05 07 December 2014 may offer a greater compatibility and reciprocity in whole tea extract as most efficient electron-scavengers compared to vitamin C (scavenger of superoxide radical) [64], vitamin E (scavenger of peroxyl radical) [65], DMSO (scavenger of hydroxyl radical) [66], or even their combination in the present study (Figures 7). The curative/remission effect of CS against arsenic is stronger than against Cu, which may be supported by the discussion in the previous paragraph that Cu cascades faster free radical reaction.…”

Flavonoids green tea against oxidant stress and inflammation with related human diseases

“…A large number of efficient polyphenolic compounds are available in whole tea extract, which has varied redox potential, lots of electron instauration and diverse electron acceptability of different types of free radicals. This may offer a greater compatibility and reciprocity in whole tea extract as most efficient electron-scavengers compared to vitamin C (scavenger of superoxide radical) [42], vitamin E (scavenger of peroxyl radical) [43] DMSO (scavenger of hydroxyl radical) [44] or even their combination as demonstrated in our previous study [13]. Especially EC and ECG which bear ortho-dihydroxyl, functionality are good antioxidants for microsomal peroxidation (Fig.…”

Heracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1

“…sprengelianum, H. persicum, H. platytaenium, H. crenatifolium, H. sphondylium, H. anisactis) hane been previously reported. The major groups of compounds found in Heracleum EOs mostly were aliphatic esters and alcohols, so as terpenoids 13,[16][17][18][19] . Literature survay on chemical characterisation of extracts (Es) of Heracleum species revealed furanocoumarins, furocoumarin dimers, coumarin glycosides, anthraquinones, stilbene and alkaloids as their main bioactive constituents [20][21][22][23] .…”