Radical hysterectomy during the transition period from traditional to nerve-sparing technique

Skręt-Magierło, Joanna; Naróg, Maciej; Kruczek, Andrzej; Kluza, Roman; Kluz, Tomasz; Magoń, Tomasz; Wicherek, Lukasz

doi:10.1016/j.ygyno.2009.11.013

Cited by 20 publications

(23 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Of these 17, 10 were conducted in mainland China [24], [25], [28], [29], [31], [32], [34]–[37], one in Taiwan [33], two in Japan [21], [23], two in Italy [22], [30], one in Poland [27] and one in the Netherlands [26]. One study included three groups [22], so we extracted only the data for the Type III NSRH group and the Type III RH group.…”

Section: Resultsmentioning

confidence: 99%

“…Two of the 13 studies involving laparotomy included in this meta-analysis were randomized controlled trials (RCTs) [28], [32], while 11 were non-randomized controlled trials [21]–[27], [29]–[31]. All 4 studies involving laparoscopy were non-randomized controlled trials.…”

Section: Resultsmentioning

confidence: 99%

“…The remaining seven studies were divided into a subgroup of two RCTs [28], [32] and a subgroup of five non-randomized studies [24], [25], [27], [29], [31]. Heterogeneity was detected, so a random-effects model was used.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Efficacy and Safety of Nerve-Sparing Radical Hysterectomy for Cervical Cancer: A Systematic Review and Meta-Analysis

et al. 2014

View full text Add to dashboard Cite

Backgroud and ObjectiveNerve-sparing radical hysterectomy (NSRH) may be associated with lower postoperative morbidity than radical hysterectomy (RH). We aimed to compare the clinical efficacy and safety of abdominal or laparoscopic NSRH and RH for treating cervical cancer through systematic review and meta-analysis.MethodsPubMed, EMBASE, The Cochrane Library and the Chinese National Knowledge Infrastructure databases were systematically searched for all relevant studies. Data were abstracted independently by two reviewers. A meta-analysis was performed to compare intra- and postoperative outcomes for the two techniques.ResultsA total of 17 clinical trials were identified. Meta-analysis showed that although operating time was significantly longer for abdominal or laparoscopic NSRH than for RH, NSRH based on laparotomy or laparoscopy proved more effective for postoperative recovery of bladder function. NSRH was also associated with lower bladder dysfunction morbidity and fewer postoperative complications. Two abdominal trials and one laparoscopic study further suggested that NSRH was associated with shorter time to recovery of anal/rectal function. In contrast, RH and NSRH based on laparotomy or laparoscopy were similar in terms of extent of resection, recurrence rate, survival rate, blood loss and frequency of intraoperative complications. The meta-analysis showed that abdominal NSRH was not significantly different from RH in length of hospital stay, while one trial suggested that length of hospital stay was shorter after laparoscopic NSRH than after the corresponding RH.ConclusionNSRH may be a reliable technique for treating early cervical cancer. Available evidence suggests that it is better than RH for postoperative recovery of pelvic organ function and postoperative morbidity, while the two techniques involve similar clinical safety and extent of resection. These results should be considered preliminary since they are based on a relatively small number of controlled trials, most of which were non-randomized. The findings should be verified in larger, well-designed studies.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Clinical Efficacy and Safety of Nerve-Sparing Radical Hysterectomy for Cervical Cancer: A Systematic Review and Meta-Analysis

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The technique of NSRH can help avoid damage of the pelvic autonomic innervation and consequently, prevent urologic and gastro-intestinal dysfunction. [19] On the other hand, NSRH may preserve not only the nerve tissue but also the cancer cells invading the nerves, so there is reasonable doubt whether the technique is not also cancer sparing. [20] Oncological efficiency of NSRH has not been fully determined and reports on its oncological outcomes are scarce and with short observation time.…”

Section: Discussionmentioning

confidence: 99%

Perineural space invasion in cervical cancer (FIGO IB1-IIB) accompanied by high-risk factors for recurrence

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…In addition, from the ability to preserve autonomic innervation of pelvic organs the so-called ''nerve-sparing'' techniques have developed [6][7][8][9], with growing popularity in surgical oncology [8][9][10][11] and deep endometriosis surgery [12,13].…”

mentioning

confidence: 99%

Laparoscopic implantation of neural electrodes on pelvic nerves: an experimental study on the obturator nerve in a chronic minipig model

et al. 2011

View full text Add to dashboard Cite

show abstract

Radical hysterectomy during the transition period from traditional to nerve-sparing technique

Cited by 20 publications

References 16 publications

Clinical Efficacy and Safety of Nerve-Sparing Radical Hysterectomy for Cervical Cancer: A Systematic Review and Meta-Analysis

Clinical Efficacy and Safety of Nerve-Sparing Radical Hysterectomy for Cervical Cancer: A Systematic Review and Meta-Analysis

Perineural space invasion in cervical cancer (FIGO IB1-IIB) accompanied by high-risk factors for recurrence

Laparoscopic implantation of neural electrodes on pelvic nerves: an experimental study on the obturator nerve in a chronic minipig model

Contact Info

Product

Resources

About