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Cited by 227 publications
(188 citation statements)
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“…We also did not identify the risk factors with a multivariate analysis. From a statistical point of view, previous reports failed to detect risk factors among the dose-function parameters because patients with RILD as an endpoint were too few to analyze with multivariate analysis and each dose-liver function parameter was not an independent variable but correlated with the other variables [3][4][5] . Therefore, instead of a multivariate analysis, we used a ROC analysis with individual monovariable analyses to assess each dose-liver function parameter, which allowed us to calculate the cutoff values with great exactness.…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations
“…We also did not identify the risk factors with a multivariate analysis. From a statistical point of view, previous reports failed to detect risk factors among the dose-function parameters because patients with RILD as an endpoint were too few to analyze with multivariate analysis and each dose-liver function parameter was not an independent variable but correlated with the other variables [3][4][5] . Therefore, instead of a multivariate analysis, we used a ROC analysis with individual monovariable analyses to assess each dose-liver function parameter, which allowed us to calculate the cutoff values with great exactness.…”
Section: Discussionmentioning
confidence: 99%
“…We believe that the prevalence of multidisciplinary treatments, including SPECT-B-3DCRT before sorafenib administration, has improved the survival of patients with advanced HCC. However, RT for HCC is limited by the occurrence of RILD [3,4] . The clinical parameters associated with RILD in this study were PS, Child classification, CLIP, and GTV.…”
Section: Discussionmentioning
confidence: 99%
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“…Liang et al proposed D mean for prediction of RILD, considering that liver received inhomogeneous dose and hepatic radiation tolerance had severe volume effect 8. In their study, D mean of 23 Gy was estimated as the hepatic radiation tolerance for primary liver cancer patients with Child‐Pugh Grade A cirrosis treated with 3DCRT, which produced a high prediction rate (72%).…”
Section: Introductionmentioning
confidence: 99%