Radiation dose to family members of hyperthyroidism and thyroid cancer patients treated with 131I

Pant, G S; Sharma, Sanjeev; Bal, Chandrasekhar; Kumar, Rakesh; Rath, G. K.

doi:10.1093/rpd/nci337

Cited by 43 publications

(29 citation statements)

References 10 publications

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“…Pant et al [8] measured the radiation dose using TLD badges until 15 days after the release of patients and reported that only 1 of 342 family members were exposed to more than 5 mSv, even though those family members cared for the patients in an isolation room and after discharge to home. The one who received more than 5 mSv (8.5 mSv) was a close relative of the patient who was disabled and unable to move.…”

Section: Discussionmentioning

confidence: 99%

Estimation of the Release Time from Isolation for Patients with Differentiated Thyroid Cancer Treated with High-dose I-131

Lee

Park

2010

Nucl Med Mol Imaging

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Purpose Patients receiving high-dose I-131 to treat differentiated thyroid cancer are isolated from visitors to limit radiation exposure to reasonable levels. The appropriate isolation time is unclear and has not been reported in Korea. The purpose of this study was to estimate the isolation time and investigate the possibility of earlier release from isolation. Methods This study was a retrospective analysis of data from 71 patients (10 men and 61 women; mean age, 49± 11.1 y) who received 3.7 GBq (47 patients), 5.55 GBq (23 patients), or 7.4 GBq (1 patient) of I-131 between January 2008 and December 2008. The radiation dose was measured with a fixed probe placed inside the isolation room. The total estimated dose equivalent (TEDE) to family members, the time required for the external dose rate to become <0.07 mSv/h, and the time required for whole-body retention to become <1.2 GBq were calculated. Results By the TEDE criterion (<5 mSv), 70 of 71 patients (98.6%) could have been released without isolation. By the external dose rate criterion, 10 of 71 (14.1%) and 60 of 71 patients (84.5%) could have been released without isolation and within 24 h, respectively. With whole-body retention criterion, 19 of 71 (26.8%) and 48 of 71 patients (67.6%) could have been released within 24 h and within 48 h, respectively. Conclusions Appropriate release times were estimated and compared using different criteria. Most patients could have been released without isolation or within 24 h of radiation treatment.

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Section: Discussionmentioning

confidence: 99%

Estimation of the Release Time from Isolation for Patients with Differentiated Thyroid Cancer Treated with High-dose I-131

Lee

Park

2010

Nucl Med Mol Imaging

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“…These are very consistent and reasonable results, because the patients were expected to show good compliance with radiation safety instructions. However, in a more large-scale study, there were some exceptional cases in which the exposures were over 1 mSv, although the usual radiation exposure was less than 1 mSv [11]. In the study, especially in the groups that used mass transport for the trip back home, 22-27% of family members showed radiation exposure of over 1 mSv.…”

Section: Discussionmentioning

confidence: 81%

“…Since the revision of the US NRC Regulatory Guide, several studies have reported that patients' release is safe for their family members, even with high-dose RIT using 3.7-5.6 GBq of 131 I [6][7][8][9][10][11]. These results are very consistent and reasonable.…”

Section: Introductionmentioning

confidence: 69%

Behavior and Awareness of Thyroid Cancer Patients in Korea Having Non-Hospitalized Low-Dose Radioiodine Treatment with Regard to Radiation Safety

Kim

Paeng

et al. 2010

Nucl Med Mol Imaging

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In many countries, including Korea, RIT is continuously increasing. Considering the radiation safety of patients' family members or the public and the convenience of patients, the pretreatment education of patients should be enhanced. In addition, the hospitalization of patients having low-dose therapy is recommended to be seriously considered and expanded, with the expansion of dedicated treatment facilities.

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“…Exposed TLDs were read with a Harshaw 6600 TLD reader. The equivalent doses were expressed in microsieverts or millisieverts, after corrected for background, by use of the dose-response (calibration) curves for 99m Tc and 131 I gamma rays (8). The radiation weighting factor for the gamma photons from both 131 I and 99m Tc was taken as 1.…”

Section: Methodsmentioning

confidence: 99%

Measurement of doses to the extremities of nuclear medicine staff

Shousha

Farag

Hassan

2010

Radiation Effects and Defects in Solids

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Medical uses of ionizing radiation now represent >95% of all man-made radiation exposure, and is the largest single radiation source after natural background radiation. Therefore, it is important to quantify the amount of radiation received by occupational individuals to optimize the working conditions for staff, and further, to compare doses in different departments to ensure compatibility with the recommended standards. For some groups working with unsealed sources in nuclear medicine units, the hands are more heavily exposed to ionizing radiation than the rest of the body. A personal dosimetry service runs extensively in Egypt. But doses to extremities have not been measured to a wide extent. The purpose of this study was to investigate the equivalent radiation doses to the fingers for five different nuclear medicine staff occupational groups for which heavy irradiation of the hands was suspected. Finger doses were measured for (1) nuclear medicine physicians, (2) technologists, (3) nurses and (4) physicists. The fifth group contains three technicians handling 131 I, while the others handled 99m Tc. Each staff member working with the radioactive material wore two thermoluminescent dosimeters (TLDs) during the whole testing period, which lasted from 1 to 4 weeks. Staff performed their work on a regular basis throughout the month, and mean annual doses were calculated for these groups. Results showed that the mean equivalent doses to the fingers of technologist, nurse and physicist groups were 30.24 ± 14.5, 30.37 ± 17.5 and 16.3 ± 7.7 μSv/GBq, respectively. Equivalent doses for the physicians could not be calculated per unit of activity because they did not handle the radiopharmaceuticals directly. Their doses were reported in millisieverts (mSv) that accumulated in one week. Similarly, the dose to the fingers of individuals in Group 5 was estimated to be 126.13 ± 38.2 μSv/GBq. The maximum average finger dose, in this study, was noted in the technologists who handled therapeutic 131 I (2.5 mSv). In conclusion, the maximum expected annual dose to extremities is less than the annual limit (500 mSv/y).

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Radiation dose to family members of hyperthyroidism and thyroid cancer patients treated with 131I

Cited by 43 publications

References 10 publications

Estimation of the Release Time from Isolation for Patients with Differentiated Thyroid Cancer Treated with High-dose I-131

Estimation of the Release Time from Isolation for Patients with Differentiated Thyroid Cancer Treated with High-dose I-131

Behavior and Awareness of Thyroid Cancer Patients in Korea Having Non-Hospitalized Low-Dose Radioiodine Treatment with Regard to Radiation Safety

Measurement of doses to the extremities of nuclear medicine staff

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