Radiation dermatitis following electron beam therapy. An evaluation of patients ten years after total skin irradiation for mycosis fungoides

Abstract

Ten patients, who had been treated for mycosis fungoides with electron beam radiation ten or more years previously, were examined for signs of radiation dermatitis. Although most patients had had acute radiation dermatitis, only a few manifested signs of mild chronic changes after having received between 1,000 and 2,800 rads.

Mycosis fungoides: radiation therapy

“…Most patients report the inability to sweat properly for 6–12 months following therapy (34) and chronically dry skin thereafter, which requires the regular use of emolliation. In long‐term follow‐up, evidence for chronic radiation dermatitis is uncommon in our experience (35). Occasional patients may display scattered telangiectasia, and rarely, these may be evident on casual examination.…”

Low- vs. Middle-dose Total Skin Electron Beam Therapy for Mycosis Fungoides: An Efficiency-based Retrospective Survey of Skin Response

“…The presence of tumours or erythroderma increases the risk of cutaneous ulcerations during TSEBT (29,30). Repeated or multiple treatments (PUVA, TSEBT or chemotherapy) may increase the risk of skin carcinoma (31), and it is interesting to note that one of our patients developed a keratoacanthoma at the end of TBEST even though a direct causal relationship is unlikely for timing reasons.…”

Choosing a systemic treatment for advanced stage cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome

“…34 Side effects of TSEB include erythema, swelling, exfoliation, tenderness, blister formation, alopecia, anhidrosis, and nail loss. 35 Effects are usually transient although hair and nail thinning may persist and skin aging is common. There is also an increased risk of developing non-melanoma skin cancers in patients who receive adjuvant PUVA or topical nitrogen mustard.…”