Quintuplets: A Rare Event Following Clomiphene Citrate Therapy

Tallon, Niamh; Case, Allison

doi:10.1016/s1701-2163(16)35178-7

Cited by 4 publications

(1 citation statement)

References 5 publications

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“…Quintuplets babies after cesarean section.Several studies have reported the use of gonadotropins (HMG) with or without clomiphene citrate for multiple pregnancies, particularly for quintuplet pregnancies[18] [19][20].…”

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confidence: 99%

Quintuplet Pregnancy: A Rare Case after Clomiphene Citrate Therapy and Review of Literature

Bambara¹,

Issa²,

Barnabé³

et al. 2019

OJOG

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Multiple pregnancies are increasing with the progress in Assisted Reproductive Technology. The authors report a case of quintuplet pregnancy after Clomiphene Citrate stimulation. This is a 28-year-old woman, G2, P1 with a 4-year-old child alive, who consulted for maternity desire. She was treated with Clomiphene Citrate at 100 mg daily for five days. The presence of a quintuplet pregnancy at 8 weeks + 5 days was found by ultrasound on 29/12/2018. During the follow up of the pregnancy, she presented pre-eclampsia from 24 th week (TA 140/100 mmHg, significant proteinuria, edema of lower limbs). Methyl Dopa treatment was instituted. Tocolytic treatment with Salbumol was prescribed facing uterine contractions at 30 weeks. The patient had premature rupture of membranes at 34 weeks + 4 days, followed by uterine contractions. She had a cesarean section at the same day with the birth of five newborns alive. This is the first reported case in Burkina Faso.

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confidence: 99%