2019
DOI: 10.1590/s0004-2803.201900000-81
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Abstract: BACKGROUND: Serotonin (5-HT) is present in the epithelial enterochromaffin cells (EC), mast cells of the lamina propria and enteric neurons. The 5-HT is involved in regulating motility, secretion, gut sensation, immune system and inflammation. OBJECTIVE: Evaluate the effects of diabetes and quercetin supplementation on serotoninergic cells and its cell loss by apoptosis in jejunal mucosa of streptozotocin-induced diabetic rats (STZ-rats). METHODS: Twenty-four male Wistar rats were divided into four groups… Show more

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Cited by 2 publications
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“…This includes protection against various diseases such as osteoporosis, certain forms of cancer, pulmonary and cardiovascular diseases but also against aging (Boots et al, 2008). The use of this antioxidant has proved to be effective in its free form, as demonstrated by previous studies with the enteric nervous system (duodenum, cecum and jejunum), at different doses of daily intake (Lopes et al, 2012;Ferreira et al, 2013;Vieira-Frez et al, 2017;de Souza et al, 2017;Martins-Perles et al, 2019).…”
Section: Introductionmentioning
confidence: 95%
“…This includes protection against various diseases such as osteoporosis, certain forms of cancer, pulmonary and cardiovascular diseases but also against aging (Boots et al, 2008). The use of this antioxidant has proved to be effective in its free form, as demonstrated by previous studies with the enteric nervous system (duodenum, cecum and jejunum), at different doses of daily intake (Lopes et al, 2012;Ferreira et al, 2013;Vieira-Frez et al, 2017;de Souza et al, 2017;Martins-Perles et al, 2019).…”
Section: Introductionmentioning
confidence: 95%