“…With respect to the trabecular bone, while most studies have employed a sort of homogenized material model, direct modeling of the trabecular microarchitecture is now available, even on standard personal computers. Such direct modeling has provided many new findings including the anisotropic characteristics due to the 3D network microarchitecture, which led to discussions of bone quality (Moon, et al, 1997, Limbert, et al, 2010, Frisardi, et al, 2012, Bin Kamisan, et al, 2016.…”