“…Microfluidic devices have demonstrated their usefulness for toxicity assays, pharmacological tests, and drug screening on various cell types, including neurons (MacKerron et al, 2017). For example, several studies have successfully investigated the pathological process within injury using compound application in microfluidic devices developed for neurological disorders (Seidi et al, 2011;Deleglise et al, , 2014Southam et al, 2013;Ruiz et al, 2014;Tran et al, 2014;Gribaudo et al, 2019;Courte et al, 2021). Thanks to their ability to isolate neurites from somas, microfluidic devices have also been used to study axonal regeneration after mechanical or chemical axotomy (Taylor et al, 2005;Tong et al, 2015;Lyu et al, 2017;Shrirao et al, 2018).…”