Quantitative high-resolution gas chromatography and mass spectrometry of toxaphene residues in fish samples

Evidence for Organochlorine Contamination in Tissues of Salmonids in Lake Tahoe

“…GC/MS conditions were as follows: splitless injection mode; He carrier gas, 35 cm/s (linear velocity); injection port, 275°C; transfer line, 285°C; ion source, 150°C. The instrument was set to monitor m/z 158.9 (dichlorotropylium cation, C H Cl> ) and its isotope 160.9 sister peak, which are characteristic fragments of toxaphene components that are not contaminated significantly by any other organochlorine compounds (Onuska and Terry, 1989;Vetter and Oehme, 1993;Buser et al, 1993).…”

Evidence for Organochlorine Contamination in Tissues of Salmonids in Lake Tahoe

“…GC/MS conditions were as follows: splitless injection mode; He carrier gas, 35 cm/s (linear velocity); injection port, 275°C; transfer line, 285°C; ion source, 150°C. The instrument was set to monitor m/z 158.9 (dichlorotropylium cation, C H Cl> ) and its isotope 160.9 sister peak, which are characteristic fragments of toxaphene components that are not contaminated significantly by any other organochlorine compounds (Onuska and Terry, 1989;Vetter and Oehme, 1993;Buser et al, 1993).…”

Characterization of Toxaphene by High Resolution Gas Chromatography Combined with High Resolution Mass Spectrometry and Tandem Mass Spectrometry

“…In order to eliminate these interferences, it has been pointed out that a resolving power higher than 20 000 is required. 27 Fragment ions at m/z 158.9768, 160.9739 and 162.9709, which correspond to the dichlorotropylium ion structure formed through a series of dechlorinations and rearrangements of CHBs, have been used in some studies 1,33,34 for the analysis of toxaphene using HRMS at a resolving power of 10 000. However, since the selected ions are fragmentation products of the molecular ions of different homologues, the identity of the original compounds cannot be known because the method is not able to distinguish between homologue groups.…”

Selective Accumulation of Polychlorocamphenes in Aquatic Biota From the Canadian Arctic

“…In some cases these differences were so pronounced that identifi- alone was problematic. Here and in other investigations, GC with electron impact or negative ion MS (GC-EIMS, GC-NIMS) has been used to establish the presence of PCCs with confidence [8][9][10][11][16][17][18][19][20][21]. Differences in GC patterns might be caused by selective accumulation of certain PCCs, either by differential uptake or metabolism.…”

Evidence for Organochlorine Contamination in Tissues of Salmonids in Lake Tahoe

“…GC/MS conditions were as follows: splitless injection mode; He carrier gas, 35 cm/s (linear velocity); injection port, 275°C; transfer line, 285°C; ion source, 150°C. The instrument was set to monitor m/z 158.9 (dichlorotropylium cation, C H Cl> ) and its isotope 160.9 sister peak, which are characteristic fragments of toxaphene components that are not contaminated significantly by any other organochlorine compounds (Onuska and Terry, 1989;Vetter and Oehme, 1993;Buser et al, 1993).…”

Characterization of Toxaphene by High Resolution Gas Chromatography Combined with High Resolution Mass Spectrometry and Tandem Mass Spectrometry

“…In order to eliminate these interferences, it has been pointed out that a resolving power higher than 20 000 is required. 27 Fragment ions at m/z 158.9768, 160.9739 and 162.9709, which correspond to the dichlorotropylium ion structure formed through a series of dechlorinations and rearrangements of CHBs, have been used in some studies 1,33,34 for the analysis of toxaphene using HRMS at a resolving power of 10 000. However, since the selected ions are fragmentation products of the molecular ions of different homologues, the identity of the original compounds cannot be known because the method is not able to distinguish between homologue groups.…”

Selective Accumulation of Polychlorocamphenes in Aquatic Biota From the Canadian Arctic

“…In some cases these differences were so pronounced that identifi- alone was problematic. Here and in other investigations, GC with electron impact or negative ion MS (GC-EIMS, GC-NIMS) has been used to establish the presence of PCCs with confidence [8][9][10][11][16][17][18][19][20][21]. Differences in GC patterns might be caused by selective accumulation of certain PCCs, either by differential uptake or metabolism.…”

Evidence for Organochlorine Contamination in Tissues of Salmonids in Lake Tahoe

“…GC/MS conditions were as follows: splitless injection mode; He carrier gas, 35 cm/s (linear velocity); injection port, 275°C; transfer line, 285°C; ion source, 150°C. The instrument was set to monitor m/z 158.9 (dichlorotropylium cation, C H Cl> ) and its isotope 160.9 sister peak, which are characteristic fragments of toxaphene components that are not contaminated significantly by any other organochlorine compounds (Onuska and Terry, 1989;Vetter and Oehme, 1993;Buser et al, 1993).…”

Characterization of Toxaphene by High Resolution Gas Chromatography Combined with High Resolution Mass Spectrometry and Tandem Mass Spectrometry

“…In order to eliminate these interferences, it has been pointed out that a resolving power higher than 20 000 is required. 27 Fragment ions at m/z 158.9768, 160.9739 and 162.9709, which correspond to the dichlorotropylium ion structure formed through a series of dechlorinations and rearrangements of CHBs, have been used in some studies 1,33,34 for the analysis of toxaphene using HRMS at a resolving power of 10 000. However, since the selected ions are fragmentation products of the molecular ions of different homologues, the identity of the original compounds cannot be known because the method is not able to distinguish between homologue groups.…”

Selective Accumulation of Polychlorocamphenes in Aquatic Biota From the Canadian Arctic

“…In some cases these differences were so pronounced that identifi- alone was problematic. Here and in other investigations, GC with electron impact or negative ion MS (GC-EIMS, GC-NIMS) has been used to establish the presence of PCCs with confidence [8][9][10][11][16][17][18][19][20][21]. Differences in GC patterns might be caused by selective accumulation of certain PCCs, either by differential uptake or metabolism.…”