Eunpyo Choi, Jung Woo Hong, Hyung-kwan Chang, Jennifer H. Shin, Jungyul Park
We present a robust microfluidic platform for stable generation of multiple chemical gradients simultaneously using in situ self-assembly of microparticles in micro channels and show the potential of the proposed system for analysis of bacterial preference for cancer cell secreting proteins. We demonstrate the proof of concept as a preferential chemotaxis assay of bacteria toward multiple chemical sources. Aspartate induces the most preferential chemotaxis over galactose and ribose. The micro fluidic device c…
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