Quantitative analysis of allergenic ingredients in eluate extracted from used denture base resin

Abstract

Allergenic ingredients extracted from used denture base resin were quantitatively analysed using a gas chromatograph/mass spectrometer and high performance liquid chromatography. Methyl methacrylate (MMA), hydroquinone (HQ), formaldehyde (FMA), benzoyl peroxide (BPO), benzoic acid (BA) and methyl benzoate (MB) were detected in a eluate from all of the dentures, while ethyleneglycol dimethacrylate (DME) was detected in the eluate from 87 dentures in use for <15 years. MMA, HQ, FMA, BPO and MB showed a decrease in correlation to the period of denture use, but continuing to be evident even after 29 years of use. The MMA showed the highest level of elution and a relatively moderate decrease over time. The elution of BA, on the contrary, showed an increase with the period of denture use up to about 10 years and subsequently reached a plateau. Our results indicate that purported allergens exist in the resin base and can be eluted into the oral cavity, even in patients using an old denture for a period of nearly 30 years.

A release of potentially toxic components from the acrylic resins for soft relining dentures

“…Cytotoxicity of phthalate, a plasticizer of acrylate materials was also demonstrated [26][27][28][29][30] . The values of the released amount of plasticizer (dBuFt) after the first day of immersion, in soft acrylate samples, are also similar.…”

“…Dokazana je i citotoksičnost ftalata, plastifikatora akrilatnim materijalima [26][27][28][29][30] . Vrednosti oslobođene količine plastifikatora (dBuFt) nakon prvog dana potapanja, u uzorcima mekih akrilata, takođe su slične.…”

A release of potentially toxic components from the acrylic resins for soft relining dentures

“…Cytotoxicity of phthalate, a plasticizer of acrylate materials was also demonstrated [26][27][28][29][30] . The values of the released amount of plasticizer (dBuFt) after the first day of immersion, in soft acrylate samples, are also similar.…”

“…Dokazana je i citotoksičnost ftalata, plastifikatora akrilatnim materijalima [26][27][28][29][30] . Vrednosti oslobođene količine plastifikatora (dBuFt) nakon prvog dana potapanja, u uzorcima mekih akrilata, takođe su slične.…”

Comparison of residual monomer loss from cold-cure orthodontic acrylic resins processed by different polymerization techniques

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Allergic complications from orthopaedic joint implants: the role of delayed hypersensitivity to benzoyl peroxide in bone cement

“…It has been postulated that, upon complete polymerization of bone cement, no traces of benzoyl peroxide should be present. However, in an analysis of dental resins used for dentures, elution of ingredients such as monomeric methyl methacrylate, hydroquinone and benzoyl peroxide over a long time period has been shown (22–24).…”

A release of potentially toxic components from the acrylic resins for soft relining dentures

“…Cytotoxicity of phthalate, a plasticizer of acrylate materials was also demonstrated [26][27][28][29][30] . The values of the released amount of plasticizer (dBuFt) after the first day of immersion, in soft acrylate samples, are also similar.…”

“…Dokazana je i citotoksičnost ftalata, plastifikatora akrilatnim materijalima [26][27][28][29][30] . Vrednosti oslobođene količine plastifikatora (dBuFt) nakon prvog dana potapanja, u uzorcima mekih akrilata, takođe su slične.…”

Comparison of residual monomer loss from cold-cure orthodontic acrylic resins processed by different polymerization techniques

“……”

Allergic complications from orthopaedic joint implants: the role of delayed hypersensitivity to benzoyl peroxide in bone cement

“…It has been postulated that, upon complete polymerization of bone cement, no traces of benzoyl peroxide should be present. However, in an analysis of dental resins used for dentures, elution of ingredients such as monomeric methyl methacrylate, hydroquinone and benzoyl peroxide over a long time period has been shown (22–24).…”

A release of potentially toxic components from the acrylic resins for soft relining dentures

“…Cytotoxicity of phthalate, a plasticizer of acrylate materials was also demonstrated [26][27][28][29][30] . The values of the released amount of plasticizer (dBuFt) after the first day of immersion, in soft acrylate samples, are also similar.…”

“…Dokazana je i citotoksičnost ftalata, plastifikatora akrilatnim materijalima [26][27][28][29][30] . Vrednosti oslobođene količine plastifikatora (dBuFt) nakon prvog dana potapanja, u uzorcima mekih akrilata, takođe su slične.…”

Comparison of residual monomer loss from cold-cure orthodontic acrylic resins processed by different polymerization techniques

“……”

Allergic complications from orthopaedic joint implants: the role of delayed hypersensitivity to benzoyl peroxide in bone cement

“…It has been postulated that, upon complete polymerization of bone cement, no traces of benzoyl peroxide should be present. However, in an analysis of dental resins used for dentures, elution of ingredients such as monomeric methyl methacrylate, hydroquinone and benzoyl peroxide over a long time period has been shown (22–24).…”