Quality of sleep and associated factors among people living with HIV/AIDS on follow up at Ethiopian Zewditu Memorial Hospital,2018

Abstract

Background: Sleep disturbance is a common complaint in people living with HIV/AIDS. Individuals with it are less likely to adhere to their treatment, have decreased quality of life, have decreased work productivity, and have increased risk of psychiatric disorders, cardiovascular morbidity, and disease progression. However, sleep condition remains under-recognized by clinicians and is not well studied in Ethiopia. Therefore it is necessary to produce scientific evidence to fill the clinical knowledge gap and recommend the focus area of management. The aim of the study was to assess sleep quality and its associated factors among people living with HIV/AIDS. Methods: An institution-based cross-sectional study was utilized among 408 participants who were selected by a systematic random sampling technique at Zewditu memorial hospital from April to May 2018. The Pittsburgh Sleep Quality Index questionnaire was used to measure sleep quality. Ethical clearance was obtained from the joint ethics committee of the University of Gondar and Amanuel Mental Specialized Hospital. Oral informed consent was obtained from each participant. Binary and multivariable logistic regression models were fitted. Odds ratios (OR) with the corresponding 95% confidence interval (95%CI) was computed to assess the strength of the association. Results: The magnitude of poor sleep quality was 55.6%. Being female [AOR=3.40, 95% CI: (1.80, 6.41)], depression [AOR =3.52, 95% CI: (1.95, 6.32)], CD4count ≤ 200 cells/mm3 [AOR=3.18,95%CI: (1.65,6.13)], duration of HIV/AIDS diagnosis [AOR=3.43,95% CI: (1.61,7.29)], current use of tobacco [AOR=5.69, 95% CI: (2.04,15.9)] and chat or caffeinated drinks [AOR=2.65, 95% CI: (1.06,6.64)] and poor sleep hygiene [AOR=3.55, 95% CI: (1.85, 6.78)] were significantly associated with poor sleep quality. Conclusions: More than half of the study participants were found to have poor sleep quality. A range factors influence quality of sleep of people with HIV/AIDS. Routine screening of sleep condition among people living with HIV/AIDS and early intervention based on the findings is suggested.

Poor sleep quality and associated factors among people attending anti-retroviral treatment clinic at Finote selam general hospital, Amhara, Ethiopia

“…The prevalence of poor sleep quality in PLWHA was 55.1% [95% CI: 50.1, 60.2] in this study. This study's findings were consistent with those of previous studies conducted in Mexico (58.6%) [ 27 ], Nigeria at Lagos State University Teaching Hospital (59.31%) [ 28 ], and Ethiopia at Zewditu Memorial Hospital (55.6%) [ 23 ],Metu hospital (57.1%) [ 29 ] and Hawassa Hospital (57.6%) [ 30 ].…”

“…The sample size was calculated using the single population proportion calculation with a 95% confidence interval, a 5% margin of error, and the prevalence of poor sleeping quality among HIV/ADIS patients (p = 55.6%) from a study conducted at Zewditu Memorial Hospital in Addis Ababa, Ethiopia [ 23 ]. The required sample size was calculated as follows: n = (Z/2) 2p (1-p)/d2 (Kelsey, 1996), n= (1.96)2(0.556) (1–0.556)/(0.05)2 = 379; adding a 10% non-response rate, the required sample size was calculated as 417 study individuals.…”

“…The questionnaire includes questions about respondents' sociodemographic characteristics, sleep quality, clinical factors, substance use, anxiety and depression, environmental factors, HIV-related perceived stigma, and social support. The Pittsburgh Sleep Quality Index (PSQI), a 19-item self-rated scale that examined Sleep Quality and disturbances over a 1-month period, was used to assess sleep quality [ 23 ]. This tool primarily addresses seven sleep components in the last month: sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.…”

Identifying subtypes of HIV/AIDS-related symptoms in China using latent profile analysis and symptom networks

“…In our study, the time since HIV/AIDS diagnosis and the duration of ART use in PWH in Profile 3 were shorter than those of their counterparts, which could make them more vulnerable to sleep disorders. Moreover, previous studies suggested a potential correlation between sleep disorders and cognitive impairment in PWH 48 , 49 . However, according to the symptom network of Profile 3 in Fig.…”

Predicting the risk of atherosclerotic cardiovascular disease among adults living with HIV/AIDS in Addis Ababa, Ethiopia: A hospital-based study

“…It was the first hospital that commenced and initiated the subsidized fee-based scheme of ART service in Ethiopia in 2003. Currently, there are about 7,674 active adults and 2,558 children in its follow-up nest [ 28 ].…”