Quality of randomized controlled trials in eating disorder prevention

Watson, Hunna J.; Goodman, Erica L.; McLagan, Nicole; Joyce, Tara; French, Elizabeth; Willan, Vivienne

doi:10.1002/eat.22712

Cited by 8 publications

(13 citation statements)

References 41 publications

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“…More recent RCTs of psychotherapy for EDs were more likely to have higher RCT‐PQRS scores. Similar findings were reported from meta‐analyses examining the quality RCTs of ED prevention (Watson et al, ) and of psychodynamic psychotherapy for a variety of mental illnesses (Kocsis et al, ). A likely explanation for this positive relationship is the implementation of quality checklists that have been developed over the years.…”

Section: Discussionsupporting

confidence: 77%

“…The development of checklists and reporting guidelines may have had an impact on improving the quality of RCTs over time. For example, Watson et al () found that the quality of 96 RCTs of prevention programs for EDs was significantly and positively associated with publication year. However, the Cochrane tool and the CONSORT guidelines do not address quality issues specific to psychotherapy trials, such as length of follow‐up, the training or supervision of therapists, adherence to treatment manuals, or consideration of therapist and/or site effects.…”

Section: Introductionmentioning

confidence: 99%

“…Previous research demonstrated that the study quality of group and individual RCTs for both depression (Cuijpers et al, ) and generalized anxiety (Cuijpers et al, ) are equivalent; however, these studies did not control for year of publication. Recall that publication year is positively associated with higher study quality (Kocsis et al, ; Watson et al, ) and that higher study quality is related to lower effect sizes (Cuijpers et al, ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The quality of randomized controlled trials of psychotherapy for eating disorders

Grenon

McKenna

Maxwell

et al. 2018

Int J Methods Psych Res

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To improve the quality of RCTs of psychotherapy of EDs, we recommend that researchers address the quality criteria listed in the RCT-PQRS. Psychotherapy trials should be registered, have a published protocol, and be reported following the Consolidated Standards of Reporting Trials guidelines. Authors should take into account the quality of the research when using that research to inform ED treatment guidelines.

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Section: Discussionsupporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The quality of randomized controlled trials of psychotherapy for eating disorders

Grenon

McKenna

Maxwell

et al. 2018

Int J Methods Psych Res

View full text Add to dashboard Cite

show abstract

“…Prevention and early intervention strategies are particularly pertinent given suggestions that neuroprogression may make symptoms more entrenched and less amenable to intervention over time [12]. A large body of research has evaluated preventative approaches for EDs, and selective prevention programs (i.e., those that target high-risk individuals/groups) have been shown to be most effective in reducing a range of psychopathology (e.g., body dissatisfaction, negative affect, and self-esteem [13,14]). These preventative approaches are informed by risk factor-related research.…”

Section: Introductionmentioning

confidence: 99%

Symptom trajectories into eating disorders: A systematic review of longitudinal, nonclinical studies in children/adolescents

et al. 2020

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Background. Eating disorders (EDs) are serious mental illnesses that can be life-threatening. Stage of illness models and early intervention strategies could be informed by a better understanding of symptomatology that precedes the onset of an ED. This review aims to explore which symptoms (both ED and other psychiatric disorder-related) exist prior to the onset of an ED and whether there any prospective associations between these symptomatologies. Methods. A systematic literature review was conducted in MEDLINE, Embase, and PsycINFO for large, longitudinal, prospective studies in nonclinical cohorts of children/adolescents that report symptoms prior to the onset of an ED. A quality assessment of included studies was conducted using the Newcastle-Ottawa Quality Assessment Scale. Results. A total of 22 studies were included, and over half were assessed to be of good quality. Studies identified the presence of a broad range of ED and other psychiatric disorder-related symptoms prior to ED onset. Possible prospective associations were identified, including early eating and feeding difficulties in childhood, to ED-related symptoms (e.g., dieting and body dissatisfaction) and other psychiatric disorder-related symptoms (e.g., anxiety and depression) in childhood/early adolescence, progressing to severe symptomatology (e.g., extreme weight control behaviors and self-harm) in mid-adolescence/emerging adulthood. Conclusion. The trajectory of symptoms identified to precede and possibly predict onset of an ED may inform early intervention strategies within the community. Suggestions for further research are provided to establish these findings and the clinical implications of these discussed, in order to inform how best to target prodromal stages of EDs.

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“…[16][17][18] However, today, there is a tendency for each research group only to evaluate data from their own field. [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38] True randomized controlled trials allow healthcare providers to make informed inferences about the validity of these trials.…”

mentioning

confidence: 99%

Detecting the extent of control over selection bias relating to oral health and otorhinolaryngology: cross-sectional study

2020

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Randomized controlled trials (RCTs) are considered to be a powerful research design for evaluating the effects of healthcare interventions. They constituted one of the most important scientific advances during the 20 th century. Through using such trials, researchers have the assurance that the differences found between the groups evaluated truly result from the effectiveness of the intervention, given that the allocation is random, i.e. there is an equal distribution of prognoses between the groups. 1-3 The controls over the allocation implementation process include generation of a random allocation sequence and simultaneous allocation concealment. 4,5 It is fundamentally important that the investigators should not be capable of anticipating the allocation of the next participants. Absence of controls over the allocation process is a major barrier to internal validity, because this allows the researcher to predict the participants' allocation at the recruitment stage. Even when bias signals are minimal, systematic differences in prognosis can be expected between the groups that will be compared. In particular, selection bias may compromise any randomized experiment in which the enrollment of subjects is sequential and the administration of treatments is unmasked. 6-9 The authors of RCTs will usually claim that they have met the randomization process criterion, in the title of the article or in the abstract. However, sequence generation schemes differ, and some schemes that are claimed to be randomized are not genuinely randomized. 10-13 Even less well understood, and often more difficult to ascertain, is whether the allocation was really concealed. Allocation concealment is actually part of the randomization process and, while distinct from the method used to generate the randomized sequence, is essential to the success of randomization. 13-15

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Quality of randomized controlled trials in eating disorder prevention

Cited by 8 publications

References 41 publications

The quality of randomized controlled trials of psychotherapy for eating disorders

The quality of randomized controlled trials of psychotherapy for eating disorders

Symptom trajectories into eating disorders: A systematic review of longitudinal, nonclinical studies in children/adolescents

Detecting the extent of control over selection bias relating to oral health and otorhinolaryngology: cross-sectional study

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