Quality of life of patients with endodontically treated teeth: A systematic review

Leong, Dephne Jack Xin; Yap, Adrian Ujin

doi:10.1111/aej.12372

Cited by 17 publications

(26 citation statements)

References 21 publications

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“…Regardless of the complex interplay between peripheral sensitization and CS, patients undergoing either nonsurgical or surgical endodontic treatment often report the alleviation of symptoms and increased quality of life 9 . Unfortunately, despite the high success rates of the alleviation of symptoms after endodontic therapy, there are approximately 5% of patients who present with persistent pain despite adequate treatment 10 .…”

Section: Significancementioning

confidence: 99%

Quantitative Assessment of Mechanical Allodynia and Central Sensitization in Endodontic Patients

Alelyani

Azar

Khan

et al. 2020

Journal of Endodontics

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Introduction: Patients seeking endodontic treatment commonly present with reduced mechanical pain thresholds (ie, mechanical allodynia [MA]) in the offending teeth. In patients with moderate to severe pain, MA may manifest in the teeth contralateral to the offending teeth because of the onset of central sensitization (CS). We hypothesize that there are quantitative differences in MA and CS in patients with different pulp and periradicular diagnoses. Methods: Patients (n 5 70) receiving endodontic treatment in the graduate endodontic clinic at the University of Texas Health Science Center at San Antonio and healthy volunteers (n 5 10) were included in this cross-sectional study. The mechanical pain threshold from molar teeth was measured by a digital bite force transducer on the offending tooth (ipsilateral) and the contralateral tooth. Ipsi-and contralateral MA among different endodontic diagnoses were analyzed using the Kruskal-Wallis with Dunn post hoc test and the Student t test for differences between sexes. Multivariate regression models analyzed predictors for MA and CS. Results: Periradicular diagnoses of asymptomatic apical periodontitis, symptomatic apical periodontitis, and chronic apical abscess cases were significantly associated with MA. CS, seen as contralateral MA, was only detected in pulpal diagnosis of symptomatic irreversible pulpitis, previously initiated treatment, symptomatic apical periodontitis, and chronic apical abscess. Females experienced significantly lower pain thresholds than males on both sides. MA and CS were significantly correlated in both sexes. The preoperative pain level and duration were significant predictors for MA and CS only in female patients. Lastly, age was a significant predictor for MA in females. Conclusions: The magnitude of MA and CS varied with different endodontic diagnoses, with CS being correlated with increases in MA. Only in female patients were age, preoperative pain duration, and intensity significant predictors for the development of MA and CS.

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Section: Significancementioning

confidence: 99%

Quantitative Assessment of Mechanical Allodynia and Central Sensitization in Endodontic Patients

Alelyani

Azar

Khan

et al. 2020

Journal of Endodontics

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“…Recent systematic reviews have demonstrated that root canal treatment can positively impact the OHR-QoL, but these reviews have also concluded that the lack of well-designed trials impairs the possibility of providing strong evidence (Antunes et al 2018, Leong & Yap 2019, Neelakantan et al 2020. In fact, most clinical trials evaluate changes on OHRQoL until only a few days after the end of endodontic treatment (Neelakantan et al 2020).…”

Section: Introductionmentioning

confidence: 99%

The impact of two root canal treatment protocols on the oral health‐related quality of life: a randomized controlled pragmatic clinical trial

Diniz‐de‐Figueiredo

Lima²,

Oliveira

et al. 2020

Int Endodontic J

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Aim To assess the impact of two root canal treatment protocols on the oral health‐related quality of life (OHRQoL) of patients in need of root canal treatment on their anterior teeth. Methodology The sample consisted of 120 participants (mean age: 34 years) enrolled in a pragmatic randomized clinical trial evaluating two root canal treatment protocols. Anterior teeth with nonvital pulps were allocated for root canal preparation with either hand files and filled with lateral compaction of gutta‐percha (manual protocol) or canal preparation with a single file in a reciprocating movement and filled with a single cone technique (Reciproc protocol). OHRQoL data were assessed using the Oral Health Impact Profile instrument (OHIP‐14), which was administered before the root canal intervention (baseline), and 6 and 12 months after treatment. Demographic and clinical characteristics of participants were collected at baseline. Data were analysed using bivariate analyses, Poisson univariate and multiple regression (α = 0.05). Results The drop‐out rate from baseline was 27% and 28% at 6 and 12 months after treatment, respectively. Both root canal protocols significantly enhanced patients' OHRQoL, regardless of the follow‐up time (P < 0.001). After 6 months, patients treated with the Reciproc protocol had significantly lower OHIP‐14 overall scores (P = 0.030), as well as significantly lower scores for psychological discomfort (P = 0.031) and social disability (P = 0.013). After 12 months, no significant difference was observed between the two root canal protocols for OHIP‐14 overall scores (P = 0.174). Either large or moderate effect sizes were observed for all domains and overall scores at both evaluation times, irrespective of the protocol. Low‐income persons (RR = 2.03) and the Reciproc protocol (RR = 1.52) had a higher likelihood of a positive impact on OHRQoL 12 months after root canal treatment. Conclusions The two root canal protocols improved the OHRQoL and differences in scores were observed only after 6 months with poorer OHRQoL for the manual protocol. After 12 months, patients with low‐income status and treated with Reciproc were associated with a greater improvement in OHRQoL scores.

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“…Equally, greater certainty is required on periapical radiolucencies that are resolving slowly, and whether they are likely to become a risk in susceptible patients. Other parameters related to quality of life and patient perceptions should also be considered in the decision‐making process before planning further treatment (Liu et al , Leong & Yap ).…”

Section: Classification Of Outcomementioning

confidence: 99%

Outcome of endodontic treatment – the elephant in the room

et al. 2020

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Quality of life of patients with endodontically treated teeth: A systematic review

Cited by 17 publications

References 21 publications

Quantitative Assessment of Mechanical Allodynia and Central Sensitization in Endodontic Patients

Quantitative Assessment of Mechanical Allodynia and Central Sensitization in Endodontic Patients

The impact of two root canal treatment protocols on the oral health‐related quality of life: a randomized controlled pragmatic clinical trial

Outcome of endodontic treatment – the elephant in the room

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