Quality of life of patients with amyotrophic lateral sclerosis

Tramonti, Francesco; Bongioanni, Paolo; Bernardo, Carolina Di; Davitti, Sara; Rossi, Bruno

doi:10.1080/13548506.2011.651149

Cited by 42 publications

(29 citation statements)

References 30 publications

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“…Depression contributes to decreased quality of life in patients with ALS (Tramonti et al, 2012), however our study indicated that as a group patients with ALS were no more likely to be depressed than a HC population. Although these results are consistent with recent reports (Averill et al, 2007; Atassi et al, 2011) that claim prevalence rates of depression are low in ALS, our study was limited by a small sample size and was not representative of a valid prevalence-rate study.…”

Section: Discussioncontrasting

confidence: 61%

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The Relationship between Depressive Symptoms, Disease State, and Cognition in Amyotrophic Lateral Sclerosis

Jelsone-Swain¹,

Persad²,

Votruba³

et al. 2012

Front. Psychology

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Cognitive impairment (CI) in amyotrophic lateral sclerosis (ALS) may present a serious barrier to a patient’s wellbeing and significantly decrease quality of life. Although reports of CI in ALS without frank dementia are becoming quite common, questions remain regarding the specific cognitive domains affected, as well as how other psychological and medical factors may impact cognitive functioning in these patients. Additionally, the influence of depressive symptoms on disease processes is not known. We aimed to address these questions by completing extensive neuropsychological tests with 22 patients with ALS and 17 healthy volunteers. A subgroup of these patients also completed questionnaires to measure depressive and vegetative symptoms. We tested for overall cognitive differences between groups, the influence of physical (e.g., bulbar and limb), vegetative (e.g., fatigue), and depressive symptoms on cognitive performance, and the relationship between depressive symptoms and disease severity in ALS. Overall, patients performed more poorly than healthy controls (HCs), most notably on tests of executive functioning and learning and memory. Results suggest that true cognitive performance differences exist between patients with ALS and HCs, as these differences were not changed by the presence of vegetative or depressive symptoms. There was no effect of limb or bulbar symptoms on cognitive functioning. Also, patients were not any more depressed than HCs, however increased depressive scores correlated with faster disease progression and decreased limb function. Collectively, it is suggested that translational advances in psychological intervention for those with CI and depression become emphasized in future research.

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Section: Discussioncontrasting

confidence: 61%

“…Like CI, research suggests that depressive symptoms in ALS may also have a negative impact on many aspects of quality of life (Tramonti et al, 2012), and could potentially affect cognition. To our knowledge however, no studies have examined the influence of depressive symptoms on cognitive performance in ALS.…”

Section: Introductionmentioning

confidence: 99%

The Relationship between Depressive Symptoms, Disease State, and Cognition in Amyotrophic Lateral Sclerosis

Jelsone-Swain¹,

Persad²,

Votruba³

et al. 2012

Front. Psychology

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“…At present, there is no cure and the only available drug (riluzole) prolongs the life of only a few months; therefore, the quality of life (QOL) changes are very useful in the meantime 2 . The interest in studying QOL of ALS patients has increased as recent studies have shown that alleviating symptoms and improving the QOL can affect the course of the disease and survival [2][3][4] . Besides, it is not obvious yet A C C E P T E D M A N U S C R I P T…”

Section: Introductionmentioning

confidence: 99%

Trends of quality of life changes in amyotrophic lateral sclerosis patients

Shamshiri

Fatehi

Abolfazli

et al. 2016

Journal of the Neurological Sciences

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“…De fato, o trabalho é uma parte importante da vida para a maioria dos adultos, e as fronteiras entre trabalho e outras esferas da vida são muito permeáveis, por exemplo, estado de humor e de satisfação no trabalho produz impactos no ambiente familiar e social [11][12][13][14].…”

Section: Discussionunclassified

Ajuste ocupacional com uso de tecnologia de comunicação em paciente com esclerose lateral amiotrófica: um autorrelato

Júnior

Malaguti

2017

Sci Med

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Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. RESUMOOBJETIVO: Este autorrelato apresenta o caso de um médico e professor universitário, portador de esclerose lateral amiotrófica avançada, e sua experiência em ajustar as atividades ocupacionais por meio de tecnologias de comunicação, como professor de ensino à distância. Trata-se de uma comunicação pessoal escrita pelo próprio paciente/professor. DESCRIÇÃO DO CASO: A disciplina de Neurofisiologia do Curso de Medicina da Universidade Federal de Juiz de Fora dinamiza as aulas presenciais com discussões de casos clínicos à distância, via plataforma de ensino virtual. Surgiu a possibilidade do professor atuar como colaborador dessa disciplina, na qual pode aproveitar sua experiência enquanto médico e sua vivência como paciente vítima de doença neuromuscular nas discussões de casos com os estudantes. Através da educação à distância, esse médico e professor supera as limitações físicas impostas pela doença. Ele tem condições de aprofundar a discussão, evidenciando os aspectos biopsicossociais, relação médico-paciente e humanização nas doenças neurodegenerativas. CONCLUSÕES: A interação com os alunos, por meio do ensino à distância, desse professor de neurofisiologia acometido por esclerose lateral amiotrófica avançada, resultou em maior interesse, maior comprometimento com o atendimento aos pacientes e melhor desempenho dos estudantes na disciplina. Também melhorou a qualidade de vida e a satisfação autorrrelatadas pelo professor, ao superar suas limitações físicas e sociais e "sentir-se útil" novamente.DESCRITORES: esclerose lateral amiotrófica; doenças neuromusculares; readaptação ao emprego; tecnologia assistiva; reabilitação. ABSTRACTAIMS: This self-report presents the case of a physician and university professor affected by amyotrophic lateral sclerosis, and his experience in adjusting his occupational activities through communication technologies, as a distance education lecturer. It is a personal communication written by the reported patient/professor. CASE DESCRIPTION: The Neurophysiology Subject at the Federal University of the Juiz de Fora Medical School includes clinical case discussions at an online teaching platform. The reported patient has been collaborating as a lecturer of this discipline following the amyotrophic lateral sclerosis diagnosis. His professional experience as a physician and personal experience as a patient with a neuromuscular disease enriches the virtual clinical discussions. Through distance education, the lecturer overcome the physical limitations imposed by his underlying condition. He is able to deepen the discussion, highlighting psychosocial aspects, doctor-patient relationship, and humanization in neurodegenerative diseases. CONCLUSIONS: The interaction with the students, through distance learning, of this neurophysiology lecturer suffering with ad...

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Quality of life of patients with amyotrophic lateral sclerosis

Cited by 42 publications

References 30 publications

The Relationship between Depressive Symptoms, Disease State, and Cognition in Amyotrophic Lateral Sclerosis

The Relationship between Depressive Symptoms, Disease State, and Cognition in Amyotrophic Lateral Sclerosis

Trends of quality of life changes in amyotrophic lateral sclerosis patients

Ajuste ocupacional com uso de tecnologia de comunicação em paciente com esclerose lateral amiotrófica: um autorrelato

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