Quality of life in patients with Takayasu's arteritis is impaired and comparable with rheumatoid arthritis and ankylosing spondylitis patients

Akar, Servet; Can, Gerçek; Binicier, Ömer Burçak; Aksu, Kenan; Akıncı, Barış; Solmaz, Dilek; Bırlık, Merih; Keser, Gökhan; Akkoç, Nurullah; Önen, Fatoş

doi:10.1007/s10067-007-0813-9

Cited by 38 publications

(27 citation statements)

References 36 publications

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“…Impaired SF-36 scores in TAK patients have been previously demonstrated in two studies (16,17). In another study of our group, we observed that all items of the SF-36 were impaired in the patients with TAK, with lower scores in the active patients (18).…”

Section: Discussionsupporting

confidence: 51%

Presence of Fibromyalgia in Patients with Takayasu's Arteritis

et al. 2013

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Objective Data regarding the frequency of fibromyalgia (FM) in patients with Takayasu's arteritis (TAK) have not been previously reported. We aimed to investigate the frequency of FM in TAK, defined according to the new 2010 ACR Preliminary Diagnostic Criteria for Fibromyalgia. The association between the ACR-1990 and 2010 FM criteria and the effects of patient-reported outcomes (PROs) on FM were also analyzed. Methods We studied 55 patients (age: 42,30±12,37 years, F/M: 49/6) with TAK and 40 age-and sexmatched controls (age: 41±10.84 years, F/M: 31/9). All patients were examined for FM tender points by two observers and asked to complete the ACR 2010 FM questionnaire for FM. The SF-36, the Health Assessment Questionnaire (HAQ) and hospital anxiety and depression scales (HADS) were used to assess the quality of life. Thirty patients were reevaluated six months later. Results Seven (12.7%) patients with TAK and four patients with HC (10%) fulfilled the 2010 FM criteria (p=0.682), while three (5.4%) TAK patients and no controls (0%) met the 1990 criteria (p=0.133). FM was found at a significantly higher rate in the active patients than in the inactive patients according to the ACR-2010 FM criteria (p=0.006). The SF-36 physical component scores were significantly lower (p=0.003) and the HAQ scores were significantly higher in the TAK (p=0.006) patients than in the controls. Conclusion The frequency of FM is similar between the general population and patients with TAK. However, the incidence of FM is significantly higher in active patients. The new FM criteria subscales (WPI, SSS) are significantly correlated with scales such as the SF-36, anxiety and depression scales and HAQ in TAK patients, suggesting that, in a minority of patients with FM and TAK, PROs may be affected by the presence of FM.

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Section: Discussionsupporting

confidence: 51%

Presence of Fibromyalgia in Patients with Takayasu's Arteritis

et al. 2013

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“…SF-36 is easy to use, acceptable to patients, and fulWls stringent criteria of reliability and validity [36], and can also distinguish physical HRQOL from mental HRQOL [17,36]. Accordingly, SF-36 has been widely used for the clinical trials in the rheumatologic conditions other than FMF [9,10,37,38]. Akar et al have demonstrated that Takayasu's arteritis patients had signiWcantly lower scores in physical and mental components of SF-36 than control group.…”

Section: Discussionmentioning

confidence: 98%

Health-related quality of life and its associations with mood condition in familial Mediterranean fever patients

et al. 2010

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The aim of the present study was to investigate the health-related quality of life (HRQOL) and mood conditions in familial Mediterranean fever (FMF) patients. Ninety FMF patients (F/M 60/30, median age 29) and 67 control subjects (F/M 46/21, median age 30) were included in this study. HRQOL was assessed with short form-36 (SF-36) and mood conditions were assessed with hospital anxiety depression scale (HADS). FMF patients had significantly lower mean scores on SF-36 physical components compared to the control group. However, mental components were comparable between groups. FMF patients were significantly more likely to have depression and anxiety compared to the control group [30 (33%) vs. 8 (12%), respectively, χ (2) = 9.58, OR (95% CI) = 3.7 (1.5-8.7), p < 0.01 for depression and 48 (53%) and 11 (16%), respectively, χ (2) = 22.31, OR (95% CI) = 5.8 (2.7-12.5), p < 0.001 for anxiety]. When frequency of anxious subjects was adjusted for the presence of concomitant depressive status as a confounding factor, the difference between the groups remained statistically significant [χ (2) = 11.86, OR (95% CI) = 5.4 (2.1-13.7), p < 0.01]. However, the difference of depression status between groups was not statistically significant when adjusted for the presence of concomitant anxiety status [χ (2) = 0.08, OR (95% CI) = 1.3 (0.5-3.8), p = 0.78] and FMF was found to be independently associated with only anxiety [OR (95% CI) = 7.1 (2.3-20.3)]. In addition, pure anxious FMF subgroup had significantly lower scores of mental health and mental component summary when compared to normal mood subgroup. In conclusion, FMF might adversely affect HRQOL. Depression and anxiety are more frequent in FMF patients than healthy subjects.

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“…A number of reports have demonstrated that TA is usually associated with immune disorders, or granulomatous diseases such as granulomatous hypophysitis, Crohn's disease, ulcerative colitis, systemic lupus erythematosus (SLE), ankylosing spondylitis (AS), rheumatoid arthritis (RA), etc. (Akar et al, 2008). Concurrent existence of these diseases seems to indicate that the onset of TA may be related to dysregulation of the immune system.…”

Section: Discussionmentioning

confidence: 99%

Takayasu’s arteritis associated with Crohn’s disease

Liu

Fang

Ruan

et al. 2009

J. Zhejiang Univ. Sci. B

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Takayasu's arteritis (TA), also known as the "pulseless disease," is a chronic vasculitis of the aorta and aortic branches. TA with Crohn's disease is rare and has not been documented in China before. In this paper we report on a case of Takayasu's arteritis associated with concurrent Crohn's disease. A 17-year-old Chinese male developed upper limb sourness and a sensation of fatigue, and his upper limb pulses were absent. He was diagnosed with TA and underwent an axillary artery bypass with autologous great saphenous vein on the left subclavian artery. After the surgery, he regained the normal blood pressure. This patient also had years of diarrhea and developed an anal canal ulcer, and was diagnosed with inflammatory bowel disease and ulcerative colitis before. Five months after the TA surgery, he was hospitalized for severe stomachache and diarrhea and was finally diagnosed with Crohn's disease. The possible pathophysiological mechanisms responsible for concurrent existence of TA and Crohn's disease may be associated with immune disorders, especially autoimmunity.

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Quality of life in patients with Takayasu's arteritis is impaired and comparable with rheumatoid arthritis and ankylosing spondylitis patients

Cited by 38 publications

References 36 publications

Presence of Fibromyalgia in Patients with Takayasu's Arteritis

Presence of Fibromyalgia in Patients with Takayasu's Arteritis

Health-related quality of life and its associations with mood condition in familial Mediterranean fever patients

Takayasu’s arteritis associated with Crohn’s disease

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