Quality of life in adults with juvenile‐onset dermatomyositis: A case–control study

Comparison of Outcomes in Adults With Pediatric‐Onset Morphea and Those With Adult‐Onset Morphea: A Cross‐Sectional Study From the Morphea in Adults and Children Cohort

“…As measured by the HRQOL scores on the SF-36, adults with pediatric-onset disease had scores that were similar to those in the age-and sex-matched general population in the United States (25). This finding contrasts with that in studies of several other rheumatic conditions in adults with pediatric-onset disease, in which overall HRQOL was found to be negatively impacted in at least some dimensions (26)(27)(28). Previous studies have shown that children with morphea have a normal self-worth and, at most, a moderate impairment in quality of life and physical function, and it appears that the relatively preserved overall HRQOL persists into adulthood (29)(30)(31).…”

Assessment of Microvascular Abnormalities by Nailfold Capillaroscopy in Juvenile Dermatomyositis After Medium‐ to Long‐Term Followup

“…Importantly, our group has found evidence for active disease in 50–73% of patients in a Norwegian juvenile DM cohort clinically examined after a median of 16.8 years of disease duration . These patients also have frequent cumulative organ damage , as well as skeletal muscle involvement and impaired quality of life , compared to sex‐ and age‐matched controls from the general population. Accordingly, the objective of the present study was to compare the presence of microvascular abnormalities in juvenile DM patients after medium‐ to long‐term disease duration with controls, using NFC and, moreover, to elucidate the possible connection between microvascular abnormalities and disease activity and other clinical characteristics.…”

“…At the followup examination, nonfasting venous blood samples were collected from patients and controls. The erythrocyte sedimentation rate was measured, and the serum concentration of the C‐reactive protein (CRP) level was analyzed with a high‐sensitivity method from serum stored at −80 ° C. Some of the data, on disease damage , disease activity , muscle measures , and health‐related quality of life have been previously published, with different numbers of patients and controls, but are included for the sake of clarity and completeness.…”

Submaximal Exercise Capacity in Juvenile Dermatomyositis after Longterm Disease: The Contribution of Muscle, Lung, and Heart Involvement

“…Outcomes may include "changes in [patients'] self-perceived health status", and "factors which are known to affect their health, well-being and quality of life" (66). Other than mortality, outcomes assessed in JDM have generally been related to disease activity and damage according to clinical scoring tools (67)(68)(69), patient reported outcome measures (PROMS) (70,71), specific organ function (72,73), and cardiorespiratory fitness (CRF) (74) (see section 1.3.1.…”