2013
DOI: 10.1038/bjc.2013.585
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Abstract: Background:Most lung cancer patients are diagnosed at an advanced disease stage and predominantly receive palliative treatment, which increasingly consists of several chemotherapy lines. We report on patients' quality of life (QOL) to gain knowledge on QOL during and across multiple lines of chemotherapy. This includes patients with (neo)adjuvant therapy up to 3rd or above line palliative chemotherapy.Methods:Lung cancer patients receiving outpatient chemotherapy at the Kufstein County Hospital completed an el… Show more

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Cited by 62 publications
(51 citation statements)
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“…The latter patients reported a substantially higher symptom burden. Similar results have been shown in a few other studies of patients with lung, pancreas, and biliary tract cancers [18][19][20]. Traditionally, objective end points such as response and survival rates have been used to evaluate the efficacy of chemotherapy in patients with advanced CRC.…”
Section: Resultssupporting
confidence: 77%
“…The latter patients reported a substantially higher symptom burden. Similar results have been shown in a few other studies of patients with lung, pancreas, and biliary tract cancers [18][19][20]. Traditionally, objective end points such as response and survival rates have been used to evaluate the efficacy of chemotherapy in patients with advanced CRC.…”
Section: Resultssupporting
confidence: 77%
“…44 Prolonged systemic chemo therapy, or the use of successive lines of chemo therapy, can be associated with cumulative toxic effects or negatively impact quality of life. [48][49][50] At present, the role of adjuvant chemo therapy after ablation of oligo metastases is unclear. Peri-operative chemotherapy improves progression-free survival in metastasis from CRC, 51 but data for most other disease sites are lacking.…”
Section: Immortal Time Biasmentioning
confidence: 99%
“…Studies also suggest that most QOL aspects remain unchanged during treatment, suggesting that palliative treatment did not negatively impact QOL. 27 So the health related QOL assessment should be done in routine clinical practice in lung cancer patients. 28 Since we measured quality of life after diagnosis, and only of those patients who had unresectable disease, the validity of our measurements can sometimes be biased by any temporary effects due to patients being informed of their diagnosis of lung cancer and possible prognosis.…”
Section: Qlq-c30 Scoresmentioning
confidence: 99%