2013
DOI: 10.1001/2013.jamadermatol.467
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Quality of Life Differences Between Responders and Nonresponders in the Treatment of Cutaneous Lupus Erythematosus

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Cited by 27 publications
(22 citation statements)
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“…Chang et al showed that treatment of CLE skin disease activity (as measured by the CLE Disease Area and Severity Index [CLASI]) correlated with an improvement in Skindex-29 emotions and symptoms subscale scores: emotions r sp =0.39 (P=0.01) and, symptoms r sp =0.33 (P=0.04). 14 In Chang’s study the correlation of the CLASI activity with the Skindex-29 functioning subscale score was not statistically significant, r sp =0.29 (P=0.07). Our study found that the correlation of cutaneous DM disease activity with quality of life measures is stronger than that of CLE and correlates with more measures (emotions, symptoms, and functioning).…”
Section: Discussionmentioning
confidence: 85%
“…Chang et al showed that treatment of CLE skin disease activity (as measured by the CLE Disease Area and Severity Index [CLASI]) correlated with an improvement in Skindex-29 emotions and symptoms subscale scores: emotions r sp =0.39 (P=0.01) and, symptoms r sp =0.33 (P=0.04). 14 In Chang’s study the correlation of the CLASI activity with the Skindex-29 functioning subscale score was not statistically significant, r sp =0.29 (P=0.07). Our study found that the correlation of cutaneous DM disease activity with quality of life measures is stronger than that of CLE and correlates with more measures (emotions, symptoms, and functioning).…”
Section: Discussionmentioning
confidence: 85%
“…The latter is especially important to consider in the assessment of these patients, as individuals with CLE have demonstrated a poorer quality of life than those with other common conditions affecting the skin [6] across multiple geographic populations [7]. Worse quality of life in CLE patients is associated with a number of factors including female gender, younger age, presence of facial lesions, and non-responsiveness to treatment [6, 8]. There are a number of other measures that have not been fully validated or utilized in international trials [9, 10].…”
Section: Evaluation Of Disease Severitymentioning
confidence: 99%
“…Treatment recommendations for CLE are eminence-based, rather than Delphi-derived recommendations (58). However, increasingly controlled trials or observational studies utilizing the CLASI are now providing evidence for approaches to treatment that can begin to address information and knowledge gaps (912). Much work is needed to improve the evidence for current approaches to evaluation and treatment, as well as to develop consensus guidelines that determine “best practices” for CLE.…”
Section: Partmentioning
confidence: 99%