Quality of life after therapy for muscle-invasive bladder cancer

Abstract

Cystectomy followed by orthotopic bladder replacement seems to keep a high level of quality of life in select cases; however, ileal conduit is still an excellent option in other patients. Bladder-sparing alternatives are available. An individual pre-therapeutic consultation will aid in determining the radical therapeutic method in each individual patient.

Quantitative risk stratification and individual comprehensive therapy for invasive bladder cancers in China

“…Numerous review articles on this topic have been published [20,21]. The most frequent conclusion is that the current body of published literature is insufficient to infer, on the basis of quality of life outcomes, that one form of diversion is superior to another because the old 'validated' questionnaire methods are challenged by face-to-face validated, individually assessed methods for measuring quality of life [22]. Furthermore, a study reveals a patient perception of a higher quality of life in 'cured' cancer patients than in the normative population of bladder cancer patients who were previously radically operated upon [23].…”

Outcomes of Radical Cystectomy in Potential Candidates for Bladder Preservation Therapy

“…Continent urinary diversion and maintained sexual function are associated with improved quality of life after RC, particularly in younger patients. 16,24 It is therefore important that patients considering BPT be counseled that if salvage RC is subsequently required, they are unlikely to receive a continent urinary diversion or nerve-sparing RC.…”

Prospective evaluation of definitive chemoradiotherapy with volumetric modulated arc therapy in patients with muscle invasive carcinoma of urinary bladder

“…Traditionally, muscle invasive bladder cancer has been treated with radical cystectomy with ileal conduit (RC) and pelvic lymph node dissection followed by adjuvant therapy depending on post-operative histopathology. However, high perioperative risks coupled with the physical and psychological impact of urinary diversion and sexual dysfunction warranted an alternative approach [ 2 , 3 ].…”