Quality of Life after Endovascular and Open AAA Repair. Results of a Randomised Triala

Prinssen, Monique; Buskens, Erik; Blankensteijn, Jan D.

doi:10.1016/j.ejvs.2003.11.006

Cited by 153 publications

(132 citation statements)

References 17 publications

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“…The conclusions we have drawn are based on a small number of subjects, however the number of subjects included in the study are similar to previously published studies [4][5][6][7][8][9][10].…”

Section: Discussionsupporting

confidence: 73%

“…Several studies have shown that shortly after the operation OR patients have a poorer HRQoL in several domains compared to EVAR patients [4][5][6][7][8][9][10]. In the present study overall NHP showed a significant decreased in HRQoL in the OR groups but not in EVAR group at one month.…”

Section: Discussionsupporting

confidence: 62%

“…In a randomised study it was found that there was a small, yet significant, HRQoL advantage for EVAR as compared to OR in the early postoperative period. At 6 months and later however, patients reported better QOL after OR than after EVAR [9]. A review article have demonstrated that the results after surgery is not consistent and there are variations between benefits for OR and EVAR [12].…”

Section: Introductionmentioning

confidence: 99%

“…One can expect that these two different treatment modalities might result in different qualities of life, in a short as well as a long term perspective. In several studies Health Related Quality of Life (HRQoL) has been examined for patients treated for AAA [4][5][6][7][8][9][10][11]. Previous studies show that patients who have been subjected to OR have more pain and have a longer hospital stay than those treated with EVAR [5,7].…”

Section: Introductionmentioning

confidence: 99%

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Health Related Quality of Life after Treatment of Abdominal Aortic Aneurysm with Open and Endovascular Techniques—A Two-Year Follow Up

Pettersson¹,

Bergbom²,

Mattsson³

2012

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Background: Patients with Abdominal Aortic Aneurysm can be treated with two different surgical methods: Open Repair (OR) or Endovascular Aortic Repair (EVAR). These two different treatments can probably result in different sense of Health Related Quality of Life, both in a short term and a long term perspective. The purpose of this prospective study was to examine patients' Health Related Quality of Life after surgical treatment of Abdominal Aortic Aneurysm over two years using different instruments for the observations. Methods: Patients were invited consecutively to answer questionnaires before operation, and 1, 12 and 24 months after surgery. The study was conducted by using the Health Related Quality of Life questionnaires Short Form (SF-36) and Nottingham Health Profile (NHP). 76 patient (40 in the OR and 36 in the EVAR group) participated in the study. The mean age in the OR group were 68 years, range 52 -80 and in the EVAR group 75 years, range 65 -85. The results from these two groups of patients were compared to a matched reference group. Results: Both patients treated with EVAR and OR rated their Health Related Quality of Life significantly lower in the domain of Mental Health in relation to a matched reference population before surgery. This difference was not present two years after intervention. After one month Health related qualities of life were worse for the OR group. After two years significant improvements in relation to baseline were observed only among patients in the OR group. No such long-term benefits were seen in the EVAR group. Conclusions: As the component Mental Health seemed to be impaired for these study groups before surgery in relation to the matched reference group, nursing and doctors care actions may be of importance during the pre-operative phase. In the short perspective Health Related Quality of Life is worse for OR patients than the EVAR group but in the long term perspective improvements beyond preoperative status can only be seen with OR patients.

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Section: Discussionsupporting

confidence: 73%

Section: Discussionsupporting

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health Related Quality of Life after Treatment of Abdominal Aortic Aneurysm with Open and Endovascular Techniques—A Two-Year Follow Up

Pettersson¹,

Bergbom²,

Mattsson³

2012

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“…The ultimate decision regarding which type of repair should be used in a given patient with an abdominal aortic aneurysm is based on a number of factors, including the quality of life expected postoperatively, cost-effectiveness, risk of sexual dysfunction, risk of aneurysm rupture, and reintervention rate. 29 These factors must be considered before a final decision is reached. Our results indicate that in patients who are candidates for both techniques, endovascular repair is preferable to open repair, given its lower rates of operative mor-n engl j med 351;16 www.nejm.org october 14 , 2004 The new england journal of medicine 1616 * The standards of the Society for Vascular Surgery/International Society for Cardiovascular Surgery were used.…”

mentioning

confidence: 99%

A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms

et al. 2004

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Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm<subtitle>A Randomized Trial</subtitle>

Lederle¹

2009

JAMA

976

545

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for the Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group E ACH YEAR IN THE UNITED STATES, 45 000 patients with unruptured abdominal aortic aneurysm (AAA) undergo elective repair, resulting in more than 1400 perioperative deaths. 1 Endovascular repair was developed to provide a less invasive method than the standard open procedure and has been reported to reduce perioperative mortality, hospital stay, and intensive care unit (ICU) stay. However, more frequent reinterventions have also been reported and the early survival advantage was lost within 2 years in previous randomized trials conducted in Europe, 2-4 leaving the preferred approach for AAA repair in doubt. Furthermore, the relative effects of the 2 procedures on quality of life and erectile function remain unclear. Devices and techniques continue to improve and operative mortalities and morbidities were relatively high in the European trials, raising the question of how relevant their results are to current US practice. We report shortterm perioperative outcomes after elective endovascular and open repair of AAA from a US multicenter randomized trial. METHODS Study Oversight The study was approved by a central human rights committee and the institutional review boards at each participating center. An independent data monitoring committee reviewed the data at regular intervals. Patients Eligible patients had AAA for which repair was planned and had (1) a maxi-Author Affiliations and Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group are listed at the end of this article.

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Quality of Life after Endovascular and Open AAA Repair. Results of a Randomised Triala

Abstract: In the early postoperative period there is a small, yet significant QoL advantage for EVAR compared to OR. At 6 months and beyond, patients reported better QoL after OR than after EVAR.

Cited by 153 publications

References 17 publications

Health Related Quality of Life after Treatment of Abdominal Aortic Aneurysm with Open and Endovascular Techniques—A Two-Year Follow Up

Health Related Quality of Life after Treatment of Abdominal Aortic Aneurysm with Open and Endovascular Techniques—A Two-Year Follow Up

A Randomized Trial Comparing Conventional and Endovascular Repair of Abdominal Aortic Aneurysms

Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm<subtitle>A Randomized Trial</subtitle>

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