Qualidade de Vida de Sobreviventes de Câncer Onco-hematológicos Submetidos ao Transplante de Células-Tronco Hematopoiéticas: Revisão Integrativa da Literatura

Vigarinho, Michele Eugênio da Silva; Domenico, Edvane Birelo Lopes De; Matsubara, Maria das Graças Silva

doi:10.32635/2176-9745.rbc.2022v68n4.2708

Cited by 3 publications

(3 citation statements)

References 32 publications

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“…Patients included in our study reported increased concerns about future fertility, both diagnosed with POF and those with residual function, and this will significantly impact present and future relationships. Comorbidities and medical conditions that may arise as short-or longterm complications of SCT, together with all other physical and psychological alterations related to initial disease and aggressive treatment, are well known to significantly impact a patient's well-being [36]. The decreased self-esteem associated with fertility issues and sexual dysfunctions, added to other possible transplant complications, will play a crucial role in the patient's recovery, social reintegration, personal and intimate relationships, and overall quality of life [6,12,37].…”

Section: Discussionmentioning

confidence: 99%

Women’s Sexual Dysfunctions Following Stem Cell Transplant and the Impact on Couple Relationship

Plotogea,

Zgura,

Mehedințu

et al. 2023

Life

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Stem cell transplant proved its efficacy in increasing the survival rate among young patients diagnosed with hematological malignancies. A transplant conditioning regimen is particularly destructive on the genital system, often determining premature ovarian failure, accompanied by vulvovaginal atrophy and sexual dysfunctions. The aims of the present study were, first, to evaluate sexual dysfunctions among transplanted women, using clinical examination and the female sexual function index (FSFI), and second, to determine their impact on a couple’s relationship. A prospective observational comparative study was performed and included 38 patients who underwent allogenic stem cell transplant (SCT) procedures for different hematological malignancies and 38 healthy patients (control group). This study included baseline evaluation, one-year, and three-year follow-up visits. In addition to anamnesis and medically obtained information, FSFI was evaluated to determine the impact of gynecological damage in a subjective manner. In the study group, vulvovaginal atrophy was diagnosed in 76.32%, with subsequent sexual dysfunctions in 92.10% of patients, based on FSFI scoring. Even though the results improved throughout the study, at the last visit, mild vulvovaginal atrophy was diagnosed in 81.58% of patients, and the FSFI score was abnormal for 21.05%. When compared to the control group, both sexual dysfunctions and FSFI results were considerably impaired, with statistical significance. There is a confirmed negative impact of sexual dysfunctions and self-declared FSFI on couple/marital status and couple relationships, with statistical significance, at the last visit. In conclusion, anatomical, functional, and psychological difficulties are a reality of long-term survivors after a stem cell transplant. They should be addressed and assessed equally to other medical conditions, as they may determine serious consequences and impact the sexual quality of life and the couple’s relationship.

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Section: Discussionmentioning

confidence: 99%

Women’s Sexual Dysfunctions Following Stem Cell Transplant and the Impact on Couple Relationship

Plotogea,

Zgura,

Mehedințu

et al. 2023

Life

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“…Added to this is the complexity, complications and discomfort caused by the disease and therapy. Thus, there is the possibility of these abrupt changes interfering with individuals' social and emotional domain and making them susceptible to the development of common mental disorders (CMD) (6) .…”

Section: Introductionmentioning

confidence: 99%

Common mental disorders in hematopoietic stem cell transplant patients: a scoping review

Almeida,

Azevedo,

Alves

et al. 2024

Rev. Bras. Enferm.

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Objective: to map common recurrent mental disorders in patients undergoing hematopoietic stem cell transplantation. Methods: this is a scoping review carried out in January 2022 in electronic databases and repositories of dissertations and thesis. Studies that answered the research question, met the objective of the study and were available in full electronically, in any language, were included. Results: the sample consisted of 28 studies, 14 of which were published in the United States of America. The common mental disorders found were depressive, anxiety, post-traumatic stress and mood disorders. Twenty symptoms were mentioned, among the most prevalent are fatigue and sleep disorders/insomnia. Conclusions: the difficulty and importance of carrying out the differential diagnosis of these disorders were highlighted, since their symptoms can be confused with other health problems and have a strong potential to interfere with patients’ evolution.

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“…Soma-se a isso a complexidade, as intercorrências e o incômodo, causados pela doença e terapia. Assim, há a possibilidade de essas mudanças abruptas interferirem no domínio social e emocional do indivíduo e torná-lo suscetível ao desenvolvimento de transtornos mentais comuns (TMC) (6) .…”

Section: Introductionunclassified

Transtornos mentais comuns em pacientes transplantados com células-tronco hematopoéticas: revisão de escopo

Almeida,

Azevedo,

Alves

et al. 2024

Rev. Bras. Enferm.

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RESUMO Objetivo: mapear os transtornos mentais comuns recorrentes em pacientes submetidos ao transplante de células-tronco hematopoéticas. Métodos: trata-se de revisão de escopo realizada em janeiro de 2022 em bases de dados eletrônicas e repositórios de dissertações e tese. Foram incluídas publicações que respondessem à questão de pesquisa, atendessem ao objetivo do estudo e que estivessem disponíveis na íntegra em meio eletrônico, em qualquer idioma. Resultados: a amostra foi composta por 28 estudos, dos quais 14 foram publicados nos Estados Unidos da América. Os transtornos mentais comuns encontrados foram os transtornos depressivos, de ansiedade, estresse pós-traumático e de humor. Foram citados 20 sintomas, entre os mais prevalentes estão a fadiga e distúrbios do sono/insônia. Conclusões: evidenciaram-se a dificuldade e a importância de realizar o diagnóstico diferencial desses transtornos, uma vez que seus sintomas podem ser confundidos com outros problemas de saúde e têm forte potencial para interferir na evolução do paciente.

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Qualidade de Vida de Sobreviventes de Câncer Onco-hematológicos Submetidos ao Transplante de Células-Tronco Hematopoiéticas: Revisão Integrativa da Literatura

Cited by 3 publications

References 32 publications

Women’s Sexual Dysfunctions Following Stem Cell Transplant and the Impact on Couple Relationship

Women’s Sexual Dysfunctions Following Stem Cell Transplant and the Impact on Couple Relationship

Common mental disorders in hematopoietic stem cell transplant patients: a scoping review

Transtornos mentais comuns em pacientes transplantados com células-tronco hematopoéticas: revisão de escopo

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