QT dispersion in comparison to Tl-201-SPECT for detection of myocardial ischaemia

Schmidt, Matthias; Schneider, Christian A.; Theissen, P.; Erdmann, Erland; Schicha, H.

doi:10.1016/j.ijcard.2005.11.044

Cited by 3 publications

(4 citation statements)

References 23 publications

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“…The findings of Schmidt and his colleagues [26] are not consistent with ours. In their study, they investigated the QTd value in the diagnosis of myocardial ischemia compared with myocardial scan using thallium 201 (Tl-201 SPECT).…”

Section: Discussioncontrasting

confidence: 87%

“…Since QT difference gives a resultant of the two values of stress and rest QTd, this can possibly be a more appropriate index for diagnosis of myocardial ischemia and the homogeneity rate of repolarization of ventricular cells [27]. Schmidt and colleagues also examined this factor in their study [26]. We found also that the cut-off for QTd in the diagnosis and prediction of the ischemia equaled 9 ms. We could conclude that under exercise-induced stress, patients who had negative stress ECG test for exerciseinduced myocardial ischemia but their QTd value was more than (9 ms), those patients most probably had abnormal perfusion scan results.…”

Section: Discussionmentioning

confidence: 82%

“…They observed that there was no significant correlation between QTd at rest and under stress and scanning parameters such as the degree of myocardial ischemia, the number of ischemic segments, and summed ischemic stress score. They gave many explanations such as differences in QT duration of up to 60 ms have been reported in individuals without structural heart disease and a significant range of overlap exists between healthy volunteers with QT dispersion of 30 ± 10 ms and patients with heart disease with 56 ± 23 ms. Another explanation may come from potentially gross interand intraobserver variability of QT dispersion assessment as reported elsewhere [26].…”

Section: Discussionmentioning

confidence: 93%

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Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study

Tahlawi

Sanad²,

Ghazal

et al. 2021

Egypt Heart J

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Background QT dispersion (QTd) is related to regional variations in myocardial repolarization. Our study aims to assess the value of QTd in prediction of myocardial ischemia and its severity during stress imaging. We enrolled one hundred patients having stable coronary artery disease (CAD) and fulfilling the “Appropriateness criteria for cardiac radionuclide imaging” (MPI). They were divided into group I including patients with MPI-detected ischemia (50 patients) and group II including patients with normal perfusion scan (50 patients). We excluded unstable CAD and all other causes affecting QTd. During isotope scan, ECGs were taken and QTd was calculated at rest and at maximum heart rate. Results QTd was significantly higher in the ischemic group both at rest and exercise (P = 0.000). QTd difference, the difference between QTd at rest and stress, was calculated. QTd difference was significantly lower in normal than in ischemic group (P = 0.003). There was a significant positive correlation between QTd difference and defect size (P = 0.04). Conclusion QTd increases in ischemia and the QTd difference (between rest and stress) correlates positively with severity of ischemia. QTd and QTd difference could be used to improve the accuracy of stress imaging test.

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Section: Discussioncontrasting

confidence: 87%

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 93%

See 1 more Smart Citation

Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study

Tahlawi

Sanad²,

Ghazal

et al. 2021

Egypt Heart J

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“…In the recently published article, Schmidt et al have reinterrogated the clinical utility of old saga, namely QT dispersion (QTD), in patients with ischemic heart disease [1]. In that study, they scrutinized the diagnostic value of QTD for the detection of myocardial ischemia in comparison to Tl-201-SPECT imaging.…”

mentioning

confidence: 99%

QT dispersion: Electrophysiological holy grail or the greatest fallacy in the surface ECG?

Çelik

İyisoy

Kurşaklıoğlu

et al. 2007

International Journal of Cardiology

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QT Dispersion at Rest and During Adenosine Stress Myocardial Perfusion Imaging Correlation with Myocardial Jeopardy Score

Vankayala²,

Niraj³

et al. 2008

Clinical Cardiology

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Background The usefulness of QT dispersion (QTd) during adenosine myocardial perfusion imaging (MPI) to predict severity of coronary artery disease (CAD) has not been studied. Methods Eighty‐eight patients referred for diagnostic cardiac catheterization after abnormal MPI were included. Thirty‐four patients with no stenosis (Duke Score = 0) were included in Group 1, and 54 patients with significant CAD (Duke Score ≥ 2) formed Group 2. Resting and stress QTd and prolongation in QTd (ΔQTd) were measured and evaluated as independent predictors for severity of CAD. Results Resting QTd was higher in Group 2 as compared with Group 1. During peak infusion of adenosine, QTd was significantly prolonged in Group 1 but remained unchanged, or fixed, in Group 2. In addition, in patients with significant CAD, resting QTd positively correlated with the Duke Score. On multiple regression analysis; independent predictors for significant CAD (odds ratio [OR], 95% confidence interval [CI], p‐value) were resting QTd (4.9, 95% CI 1.1–21.6, < 0.05 for fourth Quartile compared with first Quartile) and ΔQTd (4.0, 1.4–11.2, < 0.01 for first and second Quartiles compared with third and fourth Quartiles). Conclusion In patients with abnormal stress MPI, prolonged resting QTd, and fixation of QTd during stress are independent predictors of significant CAD. In addition, resting QTd correlate with the Duke Jeopardy Score and therefore, may have independent prognostic value. Copyright © 2008 Wiley Periodicals, Inc.

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QT dispersion in comparison to Tl-201-SPECT for detection of myocardial ischaemia

Cited by 3 publications

References 23 publications

Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study

Can QT dispersion improve the accuracy of stress ECG TMT in detecting myocardial ischemia in chronic stable CAD patients? A stress myocardial perfusion imaging study

QT dispersion: Electrophysiological holy grail or the greatest fallacy in the surface ECG?

QT Dispersion at Rest and During Adenosine Stress Myocardial Perfusion Imaging Correlation with Myocardial Jeopardy Score

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