QRS duration and left ventricular ejection fraction (LVEF) in non-ST segment elevation myocardial infarction (NSTEMI)

Clinical significance of R‐wave amplitude in lead V1 and inferobasal myocardial infarction in patients with inferior wall myocardial infarction

“…In non‐STEMI patients, Shah M et al. identified that a QRSd ≥90 ms indicates significant coronary artery involvement (Shah et al., 2016 ). Some studies correlate QRSd between 90 and 120 ms with increased cardiac volumes, reduced LVEF, and in‐hospital cardiovascular events (Taskesen et al., 2014 ).…”

“…ST‐segment elevation (ST↑) in leads V 7 –V 9 suggests a concurrent inferobasal myocardial infarction (IBMI), implying a greater myocardial injury (Adawi & Atar, 2008 ). And a prolonged QRS duration (QRSd), caused by widespread ischemia from multivessel disease, is also a predictor of worse outcomes in AMI patients (Shah et al., 2016 ). Consequently, this study seeks to explore the implications of R‐wave amplitude in lead V 1 , ST‐segment patterns in posterior chest leads, and their impact on QRSd.…”

Variations of electrocardiographic parameters during hospitalization predict long‐term outcomes in patients with non‐ST‐segment elevation myocardial infarction

“…In general, P wave could be divided into initial and terminal portions when diphasic one was present. P terminal force in lead V1 (PtfV1), mentioned the first time by Morris, Estes, Whalen, Thompson, and McIntosh (1964) and defined as terminal duration multiplied by terminal amplitude, was correlated with congestive heart failure and predictive of development of long-term MACEs in ACS (Li et al, 2015;Shah et al, 2016). Prolongation of QRS duration at the time of NSTEMI is often accompanied with a worse left ventricular function and predicts adverse long-term outcome, especially in the setting of left bundle branch block (Baslaib et al, 2010;Jimenez-Candil et al, 2008;Shah et al, 2016).…”

Subtle QRS changes are associated with reduced ejection fraction, diastolic dysfunction, and heart failure development and therapy responsiveness: Applications for artificial intelligence to ECG

“…In the MESA (Multi‐Ethnic Study of Atherosclerosis) study patients with QRS >100 ms had a risk for incident HF (Heart failure) with a HR (Hazard ratio) 2.64, 95% CI (Confidence interval), 1.66–4.2, p < .0001 (Ilkhanoff et al, 2012 ). Furthermore, Shah et al ( 2016 ) demonstrated in patients with NSTEMI (Non‐ST‐elevation myocardial infarction) a QRS ≥ 90 ms at presentation had lower LVEF, higher severe LV dysfunction at baseline and was associated with LVEF ≤35% on follow‐up with an odds ratio (OR) 2.7, 95% CI, 5.5–4.69, p < .001. Additionally, a subanalysis of the MESA Study, one of the multivariable associated with the development of HFrEF (Heart failure with reduced ejection fraction) was QRS > 100 ms (HR: 2.14, 95%CI, 1.48–3.09, p < .001; O'Neal et al, 2017 ).…”