Pyogenic liver abscess

Longworth, Sarah; Han, Michelle

doi:10.1002/cld.487

Cited by 48 publications

(76 citation statements)

References 25 publications

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“…On the other hand, the abscess with pyogenic occurs during the invasion of the liver by a germ coming through the portal vein or the artery hepatis or is secondary to biliary obstruction. This proliferation causes the destruction of the parenchyma by the formation of a purulent collection [25]. This active infection by the multiplication of bacteria promotes the occurrence of rupture.…”

Section: Pyogenic Origin Of the Abscessmentioning

confidence: 99%

Predictive risk factors for liver abscess rupture: A prospective study of 138 cases

Ndong¹,

JN²,

Na³

et al. 2020

Arch Clin Gastroenterol

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Introduction: Liver abscess is a serious condition due to its complications. The most frequent complication is rupture. Our aim is to determine the predictive risk factors of liver abscess rupture at the Saint Louis Regional Hospital Center. Material and methods: This is a prospective descriptive and analytical study over the period of 1 st January 2016 to 28 th February 2019. We included liver abscess records regardless of age. An univariate and then multivariate analysis according to a Cox model allowed us to determine the factors associated with the occurrence of rupture. Results: We collected 138 cases with 78 cases of amoebic abscess (55.3%) and 60 cases of pyogenic abscess (42.6%). We had 36 cases of rupture (26%), including 29 cases in the peritoneal cavity. The mean age was 28 years ± 18. The sex ratio (M:F) was 3.7. There were 35.5% (n= 49) of patients aged under 15 years. The mean consultation time was 18.8 days ± 4.5. The localization was the right lobe in 76.7%, the left lobe in 9.3% and bi lobar in 14%. The mean diameter of abscesses was 8 cm ± 7.5 (Range: 3.7; 16 cm). The abscesses were unique in 85.5% of cases, and sub-capsular in 15.2% of case. Gas was present in 5.7% of cases. The commonest germ found was Staphylococcus aureus in 14.5% of patients. The predictive risk factors of rupture found after univariate analysis were: diameter (p <0.001), age less than 15 years (OR= 4.3; p<0.001), pyogenic origin of abscesses (OR= 4.3, p <0.001), undernutrition (OR=2.3, p= 0.038), jaundice (OR = 4.5, p = 0.009) , left-lobe localization (OR= 7, p = 0.002), subcapsular localization (OR=8.6, p <0.001); the presence of gas (p <0.001). Multivariate analysis identifi ed 5 variables considered as independent risk factors for rupture: the pyogenic origin (HR= 22.51, p<0.001); age less than 15 years (HR= 2,296, p= 0.049); abscess diameter (HR= 1.411, p= 0.004); left lobe localization (HR= 18.68, p <0.001) and sub-capsular localization (HR= 2.689, p= 0.017). Conclusion: In our study, predictive risk factor for liver abscess rupture were: pyogenic origin, age less than 15 years, abscess diameter, left-lobe and subcapsular localization. The knowledge of these factors allows early and appropriate treatment to avoid complications.

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Section: Pyogenic Origin Of the Abscessmentioning

confidence: 99%

Predictive risk factors for liver abscess rupture: A prospective study of 138 cases

Ndong¹,

JN²,

Na³

et al. 2020

Arch Clin Gastroenterol

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“…Occasionally, when etiology cannot be identified, the term "cryptogenetic abscesses" is used. Estimates indicate that cholangitic and cryptogenetic HA are the most frequently reported (Longworth & Han, 2015) (Fig. 1).…”

Section: Pyogenic Hepatic Abscessmentioning

confidence: 99%

Morphological Characteristics of Liver Abscesses According its Etiology

Castillo

Manterola

2020

Int. J. Morphol.

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Although infrequent in the diagnostics areas, liver abscesses are of significant relevance, which is related to the high morbidity and mortality figures they can cause if they are not detected and treated in time. Although multiple operational classifications are described, the one most recognized for its usefulness is that related to its causative agent (pyogenic or bacterial infection, hydatid origin or secondary to infected hydatidosis, and amoebic or by invasive amebiasis). The objective of this article was to generate a study report regarding the morphological characteristics of liver abscesses, characterizing them according to their etiology, as well as describing their study and the latest recommended treatments.

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“…The diagnosis of hepatic abscess requires a high index of suspicion as the classic triad of fever, jaundice and right upper abdominal pain is present in a minority of cases 1. Frequently, patients present with fever and non-specific symptoms such as nausea, vomiting and malaise 1…”

Section: Descriptionmentioning

confidence: 99%