Pyoderma Gangrenosum in Childhood

Pyoderma gangrenosum in childhood - the importance of early recognition

“…At the Mayo clinic, 180 cases were diagnosed in 53 years and 4% of these were aged under 15 years [5]. In a subsequent study, 4.6% of cases were under 14 years of age [6].…”

Ulcérations extensives chez l’enfant : penser au pyoderma gangrenosum

“…Dans une série de 180 cas recensés à la Mayo Clinic, seulement 8 cas (4 %) avaient moins de 15 ans [1]. La localisation aux Tableau I Caractéristiques clinico-histologiques du pyoderma gangrenosum [4].…”

“…Le pyoderma gangrenosum (PG) est une affection cutanéo-muqueuse inflammatoire, neutrophilique, amicrobienne, de cause inconnue et d'évolution souvent chronique [1]. Il s'agit d'une dermatose rare survenant habituellement chez l'adulte mais pouvant atteindre les enfants et les nourrissons dont le début est rare avant 3 ans.…”

Neutrophilic Folliculitis and the Spectrum of Pyoderma Gangrenosum in Inflammatory Bowel Disease

“…A previous study of 44 patients with PG noted that 26 months after initiation of therapy, more than 50% of the patients continue to require long-term therapy to prevent recurrences, in both idiopathic PG and PG associated with an underlying inflammatory state [7]. Of note, bowel surgery should not be considered as therapy for skin lesions, because while total proctocolectomy for UC has been associated with both healing and lack of recurrence of PG [12,51], patients have also developed PG after total proctocolectomy [52].…”