2008
DOI: 10.1590/s0037-86822008000600020
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Abstract: Pyoderma gangrenosum is a rare inflammatory skin condition, characterized by progressive and recurrent skin ulceration. There may be rapidly enlarging, painful ulcers with undermined edges and a necrotic, hemorrhagic base. Disorders classically associated with pyoderma gangrenosum include rheumatoid arthritis, inflammatory bowel disease, paraproteinemia and myeloproliferative disorders. There have been some reports of the occurrence of pyoderma gangrenosum in Africa, and in Nigeria, but only one specifically r… Show more

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Cited by 10 publications
(8 citation statements)
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References 18 publications
(8 reference statements)
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“…Of the 17 patients on no therapy at PG onset, 16 healed, seven with first‐line therapy (topical/oral steroids ± dapsone, mesalazine (mesalamine), steroids + ciclosporin, steroid + 5‐ASA). Ten required a second‐line therapy, with nine responding.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Of the 17 patients on no therapy at PG onset, 16 healed, seven with first‐line therapy (topical/oral steroids ± dapsone, mesalazine (mesalamine), steroids + ciclosporin, steroid + 5‐ASA). Ten required a second‐line therapy, with nine responding.…”
Section: Resultsmentioning
confidence: 99%
“…20 A good response to combination therapy including steroids was seen in only five of 24 cases (<20%). The successful use of steroid was in combination therapy with dapsone in one case 21 and two cases with 5-ASA. 23,24 One case responded after addition of mesalazine to oral steroids.…”
Section: Case Series From Literature Post 2003mentioning
confidence: 99%
“…[1,2] Earlier reports from sub-Saharan Africa indicated the rarity of IBD among black Africans and from Nigeria, presence of the disease has been documented from reports of isolated cases. [3][4][5][6] At Ahmadu Bello University Teaching Hospital, Zaria, only one diagnosis had been reported in the literature in over four decades of existence [7] but within a three-year period after opening of the Gastrointestinal Surgery Unit; three cases of UC and one case of CD have been confirmed. We present these patients to illustrate some of the challenges of managing this disease in our environment.…”
Section: Introductionmentioning
confidence: 99%
“…In the United States adult population (18years and above), the overall prevalence of Inflammatory bowel disease was 478.4 per 100,000 people in 2016; the prevalence rates of Ulcerative Colitis and Crohn's Disease were 181.1 per 100,000 people and 197.7 per 100,000 people respectively [3] . Ulcerative colitis is reportedly rare in Black Africans [4,5] and indeed Nigerians [6,7,8] compared to Western populations [9,10,11] . There is no national data on the prevalence of Ulcerative Colitis in Nigeria; only few reports are available, mainly as case reports and case series [12,13,14,15] .…”
Section: Gastroenterology and Hepatology Researchmentioning
confidence: 99%