Puzzling palmar and plantar papules. Porokeratotic eccrine ostial and dermal duct nevus

Porokeratotic adnexal ostial naevus: review on the entity and therapeutic approach

“…1,5,13,14 Truncal involvement is uncommon. Some patients have coexisting problems such seizures, left hemiparesis Porokeratotic adnexal ostial naevus and scoliosis, 15 deafness and developmental delay, 16 palmoplantar keratoderma, 13 psoriasis, 17,18 hyperthyroidism and polyneuropathy, 11 breast hypoplasia 1 and KID syndrome. 19,20 Recently, PAON is considered as a mosaic form of KID as it may present mutations in a gap junction protein, connexin 26 (Cx26), encoded by the gene GJB2.…”

Porokeratotic eccrine ostial and dermal duct naevus: report of 10 cases

“…In rare instances, some abnormalities have been reported in association with PEODDN. Neurological disorders (seizures, hemiparesis and deafness), musculo‐skeletal abnormalities (scoliosis), congenital symmetrical palmoplantar keratoderma since birth, unilateral breast hypoplasia and developmental delay 6–9 have been described. None of our patients had systemic associated symptoms, so we think that the association with extracutaneous disease is uncommon.…”

Porokeratotic eccrine ostial and dermal duct naevus with dermatomal trunk involvement: literature review and report on the efficacy of laser treatment

“…A Medline search revealed 18 previously reported cases fulfilling the histological criteria of PEODDN. The main features of these 18 cases together with those of our case, which also fulfils the criteria of PEODDN, are summarized inTable 1 [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. The case reported by Marsden et al as comedone naevus of the palm demonstrated the same histological features as PEODDN and therefore has been categorized as such.…”