Pustular Psoriasis (Zumbusch)

Tolman, Maurice M.

doi:10.1001/archderm.1960.03730030058009

Cited by 22 publications

(6 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, one case report of two patients described atrophic scarring of the labia minora, mimicking the scarring caused by genital lichen sclerosus [29]. Another condition rarely seen is genital compromise with pustular psoriasis as part of a localized or generalized pustular process, but this complication has only been reported in men [1, 9, 30, 31]. Genital psoriasis can affect not only prepubertal girls, but also small children presenting localized or disseminated psoriatic eruptions in the napkin and genital area [32].…”

Section: Discussionmentioning

confidence: 99%

Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone

Guglielmetti

Conlledo

Bedoya

et al. 2012

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

IntroductionInverse psoriasis is a rare form of psoriasis that affects between 3% and 7% of the patients with psoriasis. It can comprise genital skin folds as part of genital psoriasis, and it is one of the most commonly seen dermatoses of this area. There are few evidence-based studies about the treatment of intertriginous psoriasis involving genital skin folds.Case PresentationThe authors present a 42-year-old female patient with erythematous plaques in the vulva, groin, and perianal region. The patient had previously received a broad range of topical and systemic therapies that had to be discontinued due to ineffectiveness or side effects. She was treated with 100 mg dapsone daily for 10 months, showing a significant improvement of her cutaneous and mucous lesions. Complete clearance of psoriatic lesions was observed after 4 weeks of treatment. She has remained in remission for up to 2 years, using only topical therapy with tacrolimus 0.1% and calcipotriol.DiscussionGenital psoriasis is a skin disease that causes great discomfort. It is important to include examination of the genital region and to adopt this conduct in daily clinical practice. Research in this field is still poor, making no discrimination between flexural and genital psoriasis, and is based on case series and expert opinion; therefore, empirical recommendations for the treatment of genital psoriasis remain. Dapsone has been shown to be an effective and convenient alternative for the treatment of inverse psoriasis in genital skin folds, which can provide effective control of the disease. Further studies are required to determine the efficacy and safety of current therapies, and to decide whether dapsone therapy should be considered in the management of this form of psoriasis when topical and other systemic agents are not effective.

show abstract

Section: Discussionmentioning

confidence: 99%

Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone

Guglielmetti

Conlledo

Bedoya

et al. 2012

Dermatol Ther (Heidelb)

View full text Add to dashboard Cite

show abstract

“…Although most genital psoriatic lesions represent plaque-type psoriasis, the genital area may also be affected by pustular psoriasis. Both generalised and localised pustular psoriatic eruptions may affect the genital skin (51)(52)(53). A case of a 23-year-old man with pustular psoriasis limited to the penis was described.…”

Section: Clinical Presentation [Loe: 5]mentioning

confidence: 99%

Genital Psoriasis: A Systematic Literature Review on this Hidden Skin Disease

Meeuwis¹,

Hullu²,

Massuger³

et al. 2011

Acta Derm Venerol

143

133

View full text Add to dashboard Cite

It is well known that the genital skin may be affected by psoriasis. However, little is known about the prevalence and clinical appearance of genital psoriasis, and genital skin is often neglected in the treatment of psoriatic patients. We performed an extensive systematic literature search for evidence-based data on genital psoriasis with respect to epidemiology, aetiology, clinical and histopathological presentation, diagnosis and treatment. Three bibliographical databases (PubMed, EMBASE and the Cochrane Library) were used as data sources. Fifty-nine articles on genital psoriasis were included. The results show that psoriasis frequently affects the genital skin, but that evidence-based data with respect to the efficacy and safety of treatments for genital psoriasis are extremely limited. An advised treatment paradigm for genital psoriasis, based on the levels of evidence, is: first-line: (weak) topical corticosteroids; second-line: vitamin D preparations or tar-based treatments.

show abstract

“…In SSSS, a superficial cleavage through the upper layer of the epidermis is caused by a staphylococcal-phage group II exotoxin, which is probably excreted by the mature kidney [ [84][85][86][87][88]. Its exact pathogenesis remains unknown; however, the factors that trigger an episode of generalized pustular psoriasis of von Zumbusch include topical or oral steroid use [84,[86][87][88]89], lithium [90], butazones [91], pregnancy [84], infections [84,86], ultraviolet irradiation [92,93], emo-. tional factors [87], and hypocalcemia [94].…”

mentioning

confidence: 99%

“…Its exact pathogenesis remains unknown; however, the factors that trigger an episode of generalized pustular psoriasis of von Zumbusch include topical or oral steroid use [84,[86][87][88]89], lithium [90], butazones [91], pregnancy [84], infections [84,86], ultraviolet irradiation [92,93], emo-. tional factors [87], and hypocalcemia [94]. The characteristic histopathologic lesion-the spongiform pustule of Kogoj-is a macropustule found in the upper layers of the epidermis.…”

mentioning

confidence: 99%

Dermatologic Problems in the Intensive Care Unit: Part I

Berman

Silvestri

1986

J Intensive Care Med

View full text Add to dashboard Cite

Skin disorders are present in many patients hospitalized in the intensive care unit. They range in severity from being the reason for admission to being a nuisance acquired during care These cutaneous problems have been categorized into four groups: (1) serious skin diseases that may incur life-threatening complications; (2) subtle skin findings associated with systemic disorders that may be characterized by critical events; (3) prominent cutaneous manifestations that accompany lifethreatening systemic diseases: and (4) skin disorders that develop as complications during intensive care. Diseases in the first category are discussed in this article.

show abstract

Pustular Psoriasis (Zumbusch)

Cited by 22 publications

References 16 publications

Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone

Inverse Psoriasis Involving Genital Skin Folds: Successful Therapy with Dapsone

Genital Psoriasis: A Systematic Literature Review on this Hidden Skin Disease

Dermatologic Problems in the Intensive Care Unit: Part I

Contact Info

Product

Resources

About