2021
DOI: 10.1111/jfbc.13861
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Abstract: Purple sweet potatoes extract (PSPE) have been used as a natural food antioxidant with high anthocyanin concentrations. Research investigated the lifespan and the mechanisms of PSPE on female Drosophila melanogaster. Supplementation of PSPE extended the lifespan by 16.3% and had a protective effect on injury by oxidative stress. PSPE treatment enhanced the endogenous antioxidant enzyme activity and reduced malondialdehyde (MDA) content. Furthermore, PSPE significantly up‐regulated foxo‐related genes, inhibited… Show more

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Cited by 7 publications
(2 citation statements)
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“…As shown in Figure 5c,d, the intestinal microflora was significantly reduced after administration of HE, and intestinal homeostasis was maintained. It is in line with Zhang, Wang, et al (2021), whose study reported that purple sweet potatoes extract, with high anthocyanin concentrations, could sustain intestinal homeostasis of D. melanogaster with aging. Moreover, aging and tissue damage led to abnormal proliferation and enhance terminal differentiation of ISCs.…”
Section: Discussionsupporting
confidence: 89%
See 1 more Smart Citation
“…As shown in Figure 5c,d, the intestinal microflora was significantly reduced after administration of HE, and intestinal homeostasis was maintained. It is in line with Zhang, Wang, et al (2021), whose study reported that purple sweet potatoes extract, with high anthocyanin concentrations, could sustain intestinal homeostasis of D. melanogaster with aging. Moreover, aging and tissue damage led to abnormal proliferation and enhance terminal differentiation of ISCs.…”
Section: Discussionsupporting
confidence: 89%
“…The method of lifespan determination is based on the literature (Zhang, Wang, et al, 2021). Two‐day‐old D. melanogaster was divided into 4 groups, with 10 bottles in each group and 20 flies in each bottle.…”
Section: Methodsmentioning
confidence: 99%