PURPLE (Oops! Atrophie Blanche) Revisited

Milstone, Leonard M.; Braverman, Irwin M.

doi:10.1001/archderm.134.12.1634

Cited by 9 publications

(1 citation statement)

References 3 publications

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“…37 The vessels of the vascular plexus of the deep dermis are involved only in rare occasions. 60,61 In addition to the presence of fibrinoid thrombus in the vascular lumen and sometimes the presence of fibrin on the vessel wall, in some cases, we can observe this fibrinoid material deposited in the perivascular stroma, which results in the classical clinical manifestation of "fibrinoid thrombus and fibrinoid rings" in the region of the superficial dermal vascular plexus. 21 This fibrinoid material can be clearly visualized through the PAS histochemical technique.…”

Section: Histopathological Findingsmentioning

confidence: 96%

Vasculopatia livedoide: uma doença cutânea intrigante

Criado

Rivitti

Sotto

et al. 2011

An. Bras. Dermatol.

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Livedoid vasculopathy is a skin disease that occludes the blood vessels of the dermis. It has a pauciinflammatory or non-inflammatory nature. It is characterized by the presence of macular or papular, erythematous-purpuric lesions affecting the legs, especially the ankles and feet, and producing intensely painful ulcerations, which cause white atrophic scars called "atrophie blanche". This review includes studies and case reports found in the medical literature regarding the etiopathogenic associations of the disease, particularly those related to thrombophilia, their histopathological findings and the therapeutic approaches used in the difficult clinical management of these cases. Keywords: Leg ulcer; Livedo reticularis; Thrombophilia; Thrombosis; Venous thrombosis Resumo: A vasculopatia livedoide é uma afecção cutânea oclusiva dos vasos sanguíneos da derme, de caráter pauci-inflamatório ou não-inflamatório. Caracteriza-se pela presença de lesões maculosas ou papulosas, eritêmato-purpúricas, nas pernas, especialmente nos tornozelos e pés, as quais produzem ulcerações intensamente dolorosas, que originam cicatrizes atróficas esbranquiçadas, denominadas "atrofia branca". Nesta revisão, abordamos os estudos e relatos de caso da literatura médica referentes às associações etiopatogênicas da doença, particularmente as que se referem aos estados de trombofilia, seus achados histopatológicos e abordagens terapêuticas empregadas na difícil condução clínica destes casos.

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Section: Histopathological Findingsmentioning

confidence: 96%