Purification and characterization of an agglutinin from mucus of the snail Achatina fulica

Microbe-vector Interactions in Vector-borne Diseases

“…They may, for example, explain how larval blowflies can thrive on infected human wounds, removing and killing human pathogens, such as methicillin-resistant Staphylococcus aureus (Thomas et al, 1999), and represent a whole new group of innate immune molecules awaiting investigation (see reviews by Meylears et al, 2002;Harbige, 2003). The protective role of the mucus secretions of the giant snail, Achatina fulica, a gastropod like Biomphalaria, is also enhanced by the presence of an antimicrobial factor and an agglutinin present in this secretion (Mitra et al, 1988;Ehara et al, 2002). Interestingly, the giant snail mucus contains a glycoprotein that generates H 2 O 2 , so killing bacteria (Ehara et al, 2002).…”

Microbe-vector Interactions in Vector-borne Diseases

“…They may, for example, explain how larval blowflies can thrive on infected human wounds, removing and killing human pathogens, such as methicillin-resistant Staphylococcus aureus (Thomas et al, 1999), and represent a whole new group of innate immune molecules awaiting investigation (see reviews by Meylears et al, 2002;Harbige, 2003). The protective role of the mucus secretions of the giant snail, Achatina fulica, a gastropod like Biomphalaria, is also enhanced by the presence of an antimicrobial factor and an agglutinin present in this secretion (Mitra et al, 1988;Ehara et al, 2002). Interestingly, the giant snail mucus contains a glycoprotein that generates H 2 O 2 , so killing bacteria (Ehara et al, 2002).…”

Microbe-vector Interactions in Vector-borne Diseases

“…They may, for example, explain how larval blowflies can thrive on infected human wounds, removing and killing human pathogens, such as methicillin-resistant Staphylococcus aureus (Thomas et al, 1999), and represent a whole new group of innate immune molecules awaiting investigation (see reviews by Meylears et al, 2002;Harbige, 2003). The protective role of the mucus secretions of the giant snail, Achatina fulica, a gastropod like Biomphalaria, is also enhanced by the presence of an antimicrobial factor and an agglutinin present in this secretion (Mitra et al, 1988;Ehara et al, 2002). Interestingly, the giant snail mucus contains a glycoprotein that generates H 2 O 2 , so killing bacteria (Ehara et al, 2002).…”

Microbe-vector Interactions in Vector-borne Diseases

“…They may, for example, explain how larval blowflies can thrive on infected human wounds, removing and killing human pathogens, such as methicillin-resistant Staphylococcus aureus (Thomas et al, 1999), and represent a whole new group of innate immune molecules awaiting investigation (see reviews by Meylears et al, 2002;Harbige, 2003). The protective role of the mucus secretions of the giant snail, Achatina fulica, a gastropod like Biomphalaria, is also enhanced by the presence of an antimicrobial factor and an agglutinin present in this secretion (Mitra et al, 1988;Ehara et al, 2002). Interestingly, the giant snail mucus contains a glycoprotein that generates H 2 O 2 , so killing bacteria (Ehara et al, 2002).…”