Pure Testicular Rhabdomyosarcoma

Ravich, Lawrence; Lerman, Philip H.; Drabkin, Joel W.; Foltin, E.

doi:10.1016/s0022-5347(17)63681-4

Cited by 20 publications

(3 citation statements)

References 15 publications

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“…[5] Intrascrotal sarcomas are traditionally separated into paratesticular and intratesticular tumors. [6] Paratesticular sarcomas are mostly rhabdomyosarcoma, seen in children.…”

Section: Discussionmentioning

confidence: 99%

Primary intratesticular rhabdomyosarcoma in pediatrics

et al. 2013

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Testicular sarcomas constitute only 1–2% of all testicular tumors and are mostly associated with germ cell tumor. Primary intratesticular rhabdomyosarcoma is rare and only 14 cases have been reported in the literature till date. It should be differentiated from germ cell tumor with sarcomatous component, other intratesticular spindle-cell sarcomas and paratesticular rhabdomyosarcoma. Accurate diagnosis and early treatment is essential as it is an aggressive tumor with high metastatic potential and poor prognosis. Orchidectomy is the treatment of choice. Chemo-radiotherapy is recommended in case of recurrence and metastasis.

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“…[5] Intrascrotal sarcomas are traditionally separated into paratesticular and intratesticular tumors. [6] Paratesticular sarcomas are mostly rhabdomyosarcoma, seen in children.…”

Section: Discussionmentioning

confidence: 99%

Primary intratesticular rhabdomyosarcoma in pediatrics

et al. 2013

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“…To our knowledge, 40 cases had been reported, including 15 lieomyosarcomas [11][12][13][14][15][16][17][18][19][20][21][22][23][24], seven rhabdomyosarcomas [25][26][27][28][29][30], five spindle sarcomas [31][32][33][34], four osteosarcomas [35][36][37][38], two fibrosarcomas [36,39], two pleomorphicsarcomas [33], two liposarcomas [33,40], one chondrosarcoma [3], one kaposi sarcoma [41] and one undifferentiated sarcoma [13].…”

Section: Discussionmentioning

confidence: 99%

Cytogenetic Findings of an Undifferentiated Testicular Sarcoma

et al. 2016

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Primary testicular sarcomas are extremely rare. In contrast, germ cell tumors (GCTs) with sarcomatous components (SCs) that can have similar pathologic features are more frequently reported. We report a primary undifferentiated testicular sarcoma with cytogenetic analysis for amplification of 12p. A 36-year-old male initially presented with 9.4 cm right testicular tumor and no metastatic disease. He was lost to follow-up but re-presented 2 years later with tumor growth to 21 cm and multiple pulmonary and bone metastases. Histologically, the testicular tumor revealed an undifferentiated sarcoma. Fluorescence in situ hybridization (FISH) of paraffin-embedded tissue showed no amplification of 12p. Gain of isochromosome 12p (i(12p)) is a specific chromosomal anomaly present in most GCTs. The cytogenetic analysis indicated the possibility that the tumor was not of GCT origin. This is the first report of primary testicular undifferentiated sarcoma with cytogenetic analysis for i(12p).

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“…Intratesticular sarcomas that are not associated with a germ cell tumor are very rare [6] and have been described in an older age group [6]. Most of these have been rhabdomyosarcomas [20,21,22], leiomyosarcomas [22,23], spindle cell sarcoma [22], fibrosarcoma [22], chondrosarcoma [22], and osteosarcomas [22,24]. They appear to have a better overall prognosis [6].…”

Section: Discussionmentioning

confidence: 99%

Primary Paratesticular Osteosarcoma: Case Report and A Review of the Literature

Al-Masri

Al‐Shraim

Al-Samen

et al. 2007

The Scientific World JOURNAL

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Primary paratesticular osteosarcoma is an extremely rare malignancy and, to date, only a few cases have been reported. To our knowledge, no such case arising directly from paratesticular soft tissue has been described. We describe a 52-year-old man who presented with left scrotal swelling and an excisional biopsy that revealed a sarcomatous lesion. Left inguinal orchiectomy was performed and histologic examination of the extensively sampled lesion revealed a pure paratesticular osteosarcoma. The patient died 6 months after the diagnosis with disseminated disease.

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Pure Testicular Rhabdomyosarcoma

Cited by 20 publications

References 15 publications

Primary intratesticular rhabdomyosarcoma in pediatrics

Primary intratesticular rhabdomyosarcoma in pediatrics

Cytogenetic Findings of an Undifferentiated Testicular Sarcoma

Primary Paratesticular Osteosarcoma: Case Report and A Review of the Literature

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