Pupillary Escape in Disease of the Retina or Optic Nerve

Rapid Pupil‐Based Assessment of Glaucomatous Damage

“…30 -33 The finding that variability of results with frequency doubling perimetry (FDP) does not appear to depend on the depth of glaucomatous defects may also be in part due to the larger stimulus used. 25,27,34 The Bjerrum and peripheral stimuli used in the present study cover areas of approximately 80 and 130 deg 2 , respectively, which are comparable to the stimulus size used by the FDP tests (approximately 25 to 100 deg 2 ), 34,35 and which are larger than stimuli used in techniques such as chromatic and contrast sensitivity perimetry. 36 -38 Some approximate comparisons with static automated perimetry (SAP) may be useful.…”

Rapid Pupil‐Based Assessment of Glaucomatous Damage

“…30 -33 The finding that variability of results with frequency doubling perimetry (FDP) does not appear to depend on the depth of glaucomatous defects may also be in part due to the larger stimulus used. 25,27,34 The Bjerrum and peripheral stimuli used in the present study cover areas of approximately 80 and 130 deg 2 , respectively, which are comparable to the stimulus size used by the FDP tests (approximately 25 to 100 deg 2 ), 34,35 and which are larger than stimuli used in techniques such as chromatic and contrast sensitivity perimetry. 36 -38 Some approximate comparisons with static automated perimetry (SAP) may be useful.…”

Bilateral longitudinally extensive optic perineuritis post‐COVID‐19 presenting as “idiopathic” intracranial hypertension: A case report

“…The patient's persistently worsening vision and headaches despite treatment with acetazolamide for presumed IIH prompted further evaluation, which ultimately revealed elevated CSF pressure, elevated CSF protein, and bilateral OPN on MRI. The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH 5 …”

“…The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH. 5 The relationship between COVID-19 and IIH has been sparsely reported in the literature. 6 COVID-19 may trigger a low-grade inflammatory state similar to other infections, which has been associated with a three-fold increase in IIH cases.…”

“…The presence of large pupils with sluggish reaction on initial examination suggested a bilateral optic nerve inflammatory process, ultimately identified as perineuritis. 5 Previous literature has reported that COVID-19 infection can also cause a dilated tonic pupil with poor light reflex, either unilaterally 9 or bilaterally, 10 due to injury to the postganglionic fibers of the parasympathetic innervation of the eye from the ciliary ganglion. 11 These key examination findings, along with elevated CSF protein, prompted further work-up and MRI that showed bilateral OPN.…”

Prognostic Factors for Recovery of Vision in Canine Optic Neuritis of Unknown Etiology: 26 Dogs (2003–2018)

“…The presence of PLR was associated with complete recovery of vision in this study. The PLR can be a marker of optic nerve dysfunction (103). In people, quantitative PLR assessments show significantly decreased results in acute ON (104) and correlate with the severity of damage (105, 106).…”

Rapid Pupil‐Based Assessment of Glaucomatous Damage

“…30 -33 The finding that variability of results with frequency doubling perimetry (FDP) does not appear to depend on the depth of glaucomatous defects may also be in part due to the larger stimulus used. 25,27,34 The Bjerrum and peripheral stimuli used in the present study cover areas of approximately 80 and 130 deg 2 , respectively, which are comparable to the stimulus size used by the FDP tests (approximately 25 to 100 deg 2 ), 34,35 and which are larger than stimuli used in techniques such as chromatic and contrast sensitivity perimetry. 36 -38 Some approximate comparisons with static automated perimetry (SAP) may be useful.…”

Bilateral longitudinally extensive optic perineuritis post‐COVID‐19 presenting as “idiopathic” intracranial hypertension: A case report

“…The patient's persistently worsening vision and headaches despite treatment with acetazolamide for presumed IIH prompted further evaluation, which ultimately revealed elevated CSF pressure, elevated CSF protein, and bilateral OPN on MRI. The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH 5 …”

“…The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH. 5 The relationship between COVID-19 and IIH has been sparsely reported in the literature. 6 COVID-19 may trigger a low-grade inflammatory state similar to other infections, which has been associated with a three-fold increase in IIH cases.…”

“…The presence of large pupils with sluggish reaction on initial examination suggested a bilateral optic nerve inflammatory process, ultimately identified as perineuritis. 5 Previous literature has reported that COVID-19 infection can also cause a dilated tonic pupil with poor light reflex, either unilaterally 9 or bilaterally, 10 due to injury to the postganglionic fibers of the parasympathetic innervation of the eye from the ciliary ganglion. 11 These key examination findings, along with elevated CSF protein, prompted further work-up and MRI that showed bilateral OPN.…”

Prognostic Factors for Recovery of Vision in Canine Optic Neuritis of Unknown Etiology: 26 Dogs (2003–2018)

“…The presence of PLR was associated with complete recovery of vision in this study. The PLR can be a marker of optic nerve dysfunction (103). In people, quantitative PLR assessments show significantly decreased results in acute ON (104) and correlate with the severity of damage (105, 106).…”

Rapid Pupil‐Based Assessment of Glaucomatous Damage

“…30 -33 The finding that variability of results with frequency doubling perimetry (FDP) does not appear to depend on the depth of glaucomatous defects may also be in part due to the larger stimulus used. 25,27,34 The Bjerrum and peripheral stimuli used in the present study cover areas of approximately 80 and 130 deg 2 , respectively, which are comparable to the stimulus size used by the FDP tests (approximately 25 to 100 deg 2 ), 34,35 and which are larger than stimuli used in techniques such as chromatic and contrast sensitivity perimetry. 36 -38 Some approximate comparisons with static automated perimetry (SAP) may be useful.…”

Bilateral longitudinally extensive optic perineuritis post‐COVID‐19 presenting as “idiopathic” intracranial hypertension: A case report

“…The patient's persistently worsening vision and headaches despite treatment with acetazolamide for presumed IIH prompted further evaluation, which ultimately revealed elevated CSF pressure, elevated CSF protein, and bilateral OPN on MRI. The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH 5 …”

“…The presence of large pupils with sluggish reaction on examination was also a suggestive sign of a bilateral optic nerve inflammatory process rather than IIH. 5 The relationship between COVID-19 and IIH has been sparsely reported in the literature. 6 COVID-19 may trigger a low-grade inflammatory state similar to other infections, which has been associated with a three-fold increase in IIH cases.…”

“…The presence of large pupils with sluggish reaction on initial examination suggested a bilateral optic nerve inflammatory process, ultimately identified as perineuritis. 5 Previous literature has reported that COVID-19 infection can also cause a dilated tonic pupil with poor light reflex, either unilaterally 9 or bilaterally, 10 due to injury to the postganglionic fibers of the parasympathetic innervation of the eye from the ciliary ganglion. 11 These key examination findings, along with elevated CSF protein, prompted further work-up and MRI that showed bilateral OPN.…”

Prognostic Factors for Recovery of Vision in Canine Optic Neuritis of Unknown Etiology: 26 Dogs (2003–2018)

“…The presence of PLR was associated with complete recovery of vision in this study. The PLR can be a marker of optic nerve dysfunction (103). In people, quantitative PLR assessments show significantly decreased results in acute ON (104) and correlate with the severity of damage (105, 106).…”