Punto de corte de espesor de tejido adiposo epicárdico para predecir síndrome metabólico en población venezolana

Lima-Martínez, Marcos M.; Paoli, Mariela; Donis, José H.; Odreman, Rodolfo; Torres, Christopher; Iacobellis, Gianluca

doi:10.1016/j.endonu.2013.03.004

Cited by 17 publications

(3 citation statements)

References 29 publications

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“…This finding was further supported by a positive correlation between BMI and EATT. In parallel to our findings, a sufficient number of studies have shown that EATT increased among patients with metabolic syndrome [17,18,19,20]. Increased EAT may contribute to increased incidence of coronary artery disease in this population because visceral adipose tissue is a metabolically active and may contribute to atherosclerosis by synthesizing many adipocytokines.…”

Section: Discussionsupporting

confidence: 86%

The Relationship between Epicardial Adipose Tissue Thickness and Serum Interleukin-17a Level in Patients with Isolated Metabolic Syndrome

et al. 2019

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In this study, it was aimed to investigate the relationship between the epicardial adipose tissue thickness (EATT) and serum IL-17A level insulin resistance in metabolic syndrome patients. This study enrolled a total of 160 subjects, of whom 80 were consecutive patients who applied to our outpatient clinic and were diagnosed with metabolic syndrome, and the other 80 were consecutive patients who were part of the control group with similar age and demographics in whom the metabolic syndrome was excluded. The metabolic syndrome diagnosis was made according to International Diabetes Federation (IDF)-2005 criteria. EATT was measured with transthoracic echocardiography (TTE) in the subjects. IL-17A serum levels were determined using the ELISA method. Fasting blood glucose, HDL, triglyceride, and fasting insulin levels were significantly higher in the metabolic syndrome group compared to the control group. In addition, the metabolic syndrome group had significantly higher high-sensitivity C-reactive protein (hs-CRP) and Homeostatic Model Assessment Insulin Resistance (HOMA-IR) levels than the control group. Similarly, serum IL-17A levels were significantly elevated in the metabolic syndrome group compared to the control group statistically (p < 0.001). As well, EATT was higher in the metabolic syndrome than the control group. Conclusion: By virtue of their proinflammatory properties, EATT and IL-17 may play an important role in the pathogenesis of the metabolic syndrome.

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Section: Discussionsupporting

confidence: 86%

The Relationship between Epicardial Adipose Tissue Thickness and Serum Interleukin-17a Level in Patients with Isolated Metabolic Syndrome

et al. 2019

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“…The EAT thickness found in our study participants was less compared with previous studies. [567] European middle aged men without metabolic syndrome had a mean EAT thickness of 4.1 ± 1.8 mm in the study conducted by Capristo et al . [5] This mean is significantly higher than the mean EAT thickness of our population.…”

Section: Discussionmentioning

confidence: 99%

“…Similar findings can be seen in the study done by Iacobellis and Leonetti[6] were mean thickness of EAT was found to be 7.4 ± 3 mm and 9.8 ± 4.5 mm in middle aged obese males and females respectively. Recently reported cut off point of EAT thickness for predicting metabolic syndrome in Venezuelan population[7] is more than 5 mm. This brings us to a question whether epicardial fat accumulation begins in later age unlike VF?…”

Section: Discussionmentioning

confidence: 99%