Punctate porokeratosis

Himmelstein, R.

doi:10.1001/archderm.120.2.263

Cited by 16 publications

(11 citation statements)

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“…Porokeratosis punctata palmaris et plantaris is clinically and histopathologically similar to the lesions on the palms and soles in case 2. The gross appearance of the lesions was reminiscent of the ‘keratotic projections’ or ‘keratotic plugs’ described in porokeratosis punctata [16,17,18,19]. Histopathologically, some keratinocytes had perinuclear haloes, which could simulate the vacuolisation that is typical of porokeratosis.…”

Section: Discussionmentioning

confidence: 93%

Two Case Reports of Columnar Dyskeratosis, an Unusual Keratinisation Disorder

Pock¹,

Štork

2010

Dermatology

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Keratinisation disorders with distinctive histopathological patterns are few in number. We describe two men with unusual dermatosis, characterised by a distinctive pattern of focal dyskeratosis. Both men suffered from generalised dermatosis formed by verrucous red-brown plaques. Repeated skin biopsies showed the same histopathological pattern with foci of vertically oriented dyskeratotic cells. The dyskeratotic cells on the level of the stratum spinosum and granulosum were positive for AE1/AE3, CK-HW, CK-LS and CK116 immunostaining. PCR for HPV was negative. The similar clinical appearance of skin lesions in both patients together with their identical histopathological pictures seems to represent a unique clinicopathological condition that we believe is best described by the term ‘columnar dyskeratosis’.

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Section: Discussionmentioning

confidence: 93%

Two Case Reports of Columnar Dyskeratosis, an Unusual Keratinisation Disorder

Pock¹,

Štork

2010

Dermatology

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“…2,4 Punctate porokeratotic keratoderma and spiny keratoderma are also worth considering. It is also worth keeping in mind porokeratotic eccrine ostial and dermal duct nevus (PEODDN), a rare congenital hamartoma of eccrine origin, which may be clinically indistinguishable from PP, although on histological examination it shows multiple cornoid lamella-like parakeratotic columns, associated exclusively with the eccrine duct and ostia.…”

Section: Discussionmentioning

confidence: 99%

“…Managing PP involves topical treatment such as urea, salicylic acid, and retinoids. 4,6 Beyond the aesthetic aspect there are no other concerns associated with PP, namely an increased risk of cutaneous cancer.…”

Section: Discussionmentioning

confidence: 99%

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Unilateral punctate porokeratosis - Case report

Teixeira

Reis

Vieira

et al. 2013

An. Bras. Dermatol.

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This case report involves a 20-year-old man with unilateral punctate porokeratosis. The patient presented an 8-year history of numerous asymptomatic keratotic papules and pits with linear distribution on his left pal-mar surface and fifth finger of the left hand. Histopathological examination of the keratotic plug revealed findings of distinct epidermal depressions containing cornoid lamellae. This report review draws attention to differential diagnoses of punctate porokeratosis.

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“…Brown [1] first described a similar case in 1971, calling it 'punctate kerato- derma' and 2 years later Herman [2] reported a case of 'punctate porokeratotic keratoderma' in a 50-year-old man. Other terms include 'punctate porokeratosis' [3], 'punctate porokeratosis of the palms and soles' [4] and 'hyperkératose palmoplantaire filiforme' [5,6].…”

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confidence: 99%