Punctate keratoderma

Spiny Keratoderma: A Common Under‐Reported Dermatosis

“…Also interesting is that the occupations of five patients of our series required manual labor, a finding which may be a factor as mentioned in the first recorded case by Brown (1). Kondo (10) has analyzed keratotic plugs and identified keratin 6 and 16 in the keratotic plugs, which are marker polypeptides of proliferating cells, thus indicating hyperproliferation and incomplete keratinization (parakeratosis), that may somehow be related to repeated trauma.…”

“…We agree with Osman (11) who first coined the term "spiny keratoderma," the disorder is a very localized keratoderma, and, clinically appears as spiny projections. Confusion with porokeratosis should not be made; although both demonstrate a thin column of parakeratotic cells with a thin granular layer beneath the column (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13), spiny keratoderma histologically does not demonstrate vacuolization and/or dyskeratosis of the underlying spinous layer, forming the so-called cornoid lamella (7,8,(10)(11)(12).…”

I have spikes on my hands

“…Familial spiny keratoderma (FSK) has been classified as type II punctate palmoplantar keratoderma (PPK), and has an autosomal dominant inheritance pattern. 1,4 It is largely recognized as a benign condition, and the reported age of onset ranges from puberty to 45 years. 5,6 Acquired spiny keratoderma (ASK) has a similar age of onset, but has a paraneoplastic pattern in roughly 50% of those diagnosed.…”

Unilateral punctate porokeratosis - Case report

“…1 Punctate porokeratotic keratoderma (palmaris et plantaris), spiny keratoderma and punctate porokeratosis (palmaris et plantaris) are frequently referred to indiscriminately as if they referred to the same assumption. 2-4 More recent publications have however highlighted major distinctions between these descriptions.…”