Pulmonary Vascular Manifestations of COVID-19                     Pneumonia

Lang, Min; Som, Avik; Carey, Denston; Reid, Nicholas; Mendoza, Dexter P.; Flores, Efrén J.; Li, Matthew; Shepard, Jo-Anne O.; Little, Brent P.

doi:10.1148/ryct.2020200277

Cited by 131 publications

(177 citation statements)

References 51 publications

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“…Of note, description of pulmonary vascular manifestations of Covid-19 pneumonia using DECT has been previously reported [7,8]. Radiological findings were mosaic perfusion patterns, vessel enlargement within and outside of lung opacities as well as peripheral perfusion defects with surrounding halos of increased perfusion [7,8]. These results are to a certain extent consistent with our findings.…”

Section: To the Editorsupporting

confidence: 92%

In vivo demonstration of pulmonary microvascular involvement in COVID-19 using dual-energy computed tomography

et al. 2020

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Section: To the Editorsupporting

confidence: 92%

In vivo demonstration of pulmonary microvascular involvement in COVID-19 using dual-energy computed tomography

et al. 2020

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“…Instead, CTPA should be reserved to patients with significantly elevated D-dimer on admission (2000-4000 μg/ml) or with significant D-dimer increase during the hospital stay. 80 Dual energy CT may be useful for the evaluation of lung perfusion abnormalities in COVID-19 patients not only in the acute setting 81 but also to monitor lung sequelae in follow-up scans.…”

Section: Role Of Ct In the Detection Of Acute Pulmonary Embolism In Cmentioning

confidence: 99%

Role of computed tomography in COVID-19

Pontone

Scafuri

Mancini

et al. 2021

Journal of Cardiovascular Computed Tomography

115

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Coronavirus disease 2019 (COVID-19) has become a rapid worldwide pandemic. While COVID-19 primarily manifests as an interstitial pneumonia and severe acute respiratory distress syndrome, severe involvement of other organs has been documented. In this article, we will review the role of non-contrast chest computed tomography in the diagnosis, follow-up and prognosis of patients affected by COVID-19 pneumonia with a detailed description of the imaging findings that may be encountered. Given that patients with COVID-19 may also suffer from coagulopathy, we will discuss the role of CT pulmonary angiography in the detection of acute pulmonary embolism. Finally, we will describe more advanced applications of CT in the differential diagnosis of myocardial injury with an emphasis on ruling out acute coronary syndrome and myocarditis.

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“…The early onset of of angiogenesis in COVID-19 pathogenesis has yet to be confirmed. However, our observations from dual energy CT and those of others have revealed perfusion defects even in patients with mild (non-ICU) COVID-19 (7). Hence, CT findings (such as vascular tree-in-bud or DECT perfusion abnormalities) might provide a vital non-invasive 'window' to better highlight disease progression and/or ascertain the beneficial or deleterious treatment responses to therapeutic strategies such as CP.…”

Section: To the Editormentioning

confidence: 57%