Pulmonary sarcoidosis and focal segmental glomerulosclerosis: case report and renal transplant follow-up.

Veronese, Francisco José Veríssimo; Henn, Lucélia de Azevedo; Faccin, Carlo Sasso; Mussatto, A V; Neto, Arlete; Edelweiss, Maria Isabel Albano; Morales, J V

doi:10.1093/oxfordjournals.ndt.a027855

Cited by 8 publications

(3 citation statements)

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“…After 5 months, the proteinuria disappeared and corticosteroid therapy was progressively reduced and discontinued. Two similar cases, one reported by Hakaim et al [6]and the other by Veronese et al [7], had the diagnosis of pulmonary sarcoidosis simultaneously to sarcoidosis due to FSGS. During their follow-up pulmonary sarcoidosis remained in remission with corticosteroid therapy; however, FSGS progressed to end-stage renal failure and they received living-related renal transplants.…”

Section: Discussionmentioning

confidence: 87%

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A Rare Cause of Focal Segmental Glomerulosclerosis: Sarcoidosis

Altıparmak

Oygar²,

Bilir³

et al. 2002

Nephron

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A 58-year-old female patient diagnosed as having sarcoidosis 23 years ago developed nephrotic syndrome. No pathology was found which could explain this, so it was attributed to her sarcoidosis. Renal biopsy showed global and segmental sclerosis. The occurrence of focal segmentary glomerulosclerosis in a case of sarcoidosis is rare. In systemic sarcoidosis it is thought that T-cell dysfunction may play a role in the pathogenesis of glomerulonephritis. When treatment is considered, corticosteroid therapy may be used according to the clinical status at diagnosis as well as on follow-up of the patient.

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Section: Discussionmentioning

confidence: 87%

“…Therefore, nephrotic syndrome is thought to be mainly due to renal involvement of sarcoidosis. A total of 5 cases of nephrotic syndrome with FSGS associated with sarcoidosis have been reported [5, 6, 7, 8, 9]. One of the cases reported by Peces et al [5]had active pulmonary sarcoidosis and nephrotic syndrome secondary to FSGS.…”

Section: Discussionmentioning

confidence: 99%

A Rare Cause of Focal Segmental Glomerulosclerosis: Sarcoidosis

Altıparmak

Oygar²,

Bilir³

et al. 2002

Nephron

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“…This innovative TACE-based therapy is a special type of chemoembolization used to block the short blood vessels that supply the liver (hepatic artery) with oxygenated blood while treating cancer ( 15 , 16 ). TACE can be performed using two techniques: conventional TACE (cTACE) and TACE-based drug-eluting beads (DEB-TACE) ( 17 ). By delivering various small-molecular chemotherapeutic drugs and embolic agents to the blood supply arteries of hepatocellular carcinoma, it controls the tumor growth by blocking the blood supply to the tumor site and causing ischemia and hypoxia ( 4 ).…”

Section: Discussionmentioning

confidence: 99%

Transcatheter arterial chemoembolization of apatinib and camrelizumab (SHR1210) against liver metastasis from hepatic neuroendocrine tumor: a case report

Qi,

Yang,

Zhu

et al. 2024

Front. Oncol.

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In this case report, we present the case of a 46-year-old woman with a hepatic neuroendocrine tumor (NET G2)-induced liver metastases. Initially, the left lateral lobectomy of the liver was performed. The post-operative pathological examination revealed NET G2, leading to the post-operative recovery with a general review. Further, the re-examination of liver magnetic resonance imaging (MRI) showed post-operative changes in the tumor of the left lateral lobe, with multiple liver masses and possible metastasis. Thus, the liver interventional therapy and apatinib-based targeted therapy based on the “camrelizumab + apatinib” regimen were performed, respectively. The 20-month follow-up indicated a slightly increased hepatic hilum and retroperitoneal lymph nodes, accompanied by hand-foot syndrome. Eventually, the overall condition continued to relieve, indicating that the combined treatment could substantially improve the NET G2 conditions-associated liver metastasis.

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