2006
DOI: 10.1055/s-2005-872855 View full text |Buy / Rent full text
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Abstract: With pulmonary metastases of osteosarcoma, every attempt should be made to completely resect all clinically detected metastases. Repeat thoracotomy in recurrent disease is compatible with long-term survival.

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“…Several studies concerning surgery for pulmonary metastases from pediatric solid tumors have been published and the 5-year survival rates reported ranged from 20% to 40% [6,7,21]. In the present studies, patients with complete resection of all pulmonary metastases had a 5-year survival probability of 28% which compares with other studies and confirms the poor prognosis of these patients with metastatic disease.…”
Section: Discussionsupporting
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rupbmjkragerfmgwileyiopcupepmcmbcthiemesagefrontiersapsiucrarxivemeralduhksmucshluniversity-of-gavle
“…Several studies concerning surgery for pulmonary metastases from pediatric solid tumors have been published and the 5-year survival rates reported ranged from 20% to 40% [6,7,21]. In the present studies, patients with complete resection of all pulmonary metastases had a 5-year survival probability of 28% which compares with other studies and confirms the poor prognosis of these patients with metastatic disease.…”
Section: Discussionsupporting
“…The complete resection has been reported to be a better prognostic factor for OS in many studies [3,6,15]. In our study, univariate analysis showed the significant difference in OS as Overall survival for patients concerning pulmonary metastases identified during chemotherapy.…”
Section: Discussionmentioning
“…Some reports show that there was no difference in survival between younger and older people [1,3,5,8]. But our results show that patients aged > 15 years had a better prognosis than patients aged ≤ 15 years.…”
Section: Discussioncontrasting
“…To this end, we assessed the impact of age, sex, number of metastases at first metastasectomy, maximal diameter of the tumor at first pulmonary metastasectomy, number of surgeries, and DFI on survival. In a previous systematic review of reported outcome in approximately 1,800 osteosarcoma patients with pulmonary metastases from 1939 to 2007, the main prognostic factor affecting survival was found to be complete surgical remission [1,[4][5][6]8]. In addition, DFI, as well as number and localization of metastases, has also been found to be significantly associated with survival [3,[5][6][7][9][10][11].…”
Section: Discussionmentioning
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