Pulmonary Edema Associated With Upper Airway Obstruction

Pediatric negative pressure pulmonary edema: Case series and review of the literature

“…NPPE is thought to be more common in young and fit individuals that may produce significant negative pressures. 5 Supporting previous reports, in our series, two patients that were avid athletes developed NPPE after brief episode of airway obstruction. Interestingly, 2/7 were obese.…”

“…NPPE is a rare but serious complication that develops rapidly at the onset or at the relief of acute upper airway obstruction (UAO) in a spontaneously breathing patient. [3][4][5] The pathophysiology of NPPE stems from the markedly negative thoracic pressure induced by inspiratory effort against an obstructed upper airway.…”

The use of extracorporeal membrane oxygenation in a child with adult respiratory distress syndrome following post‐obstruction pulmonary oedema

“…Post-obstruction pulmonary oedema was first described in 1977(Newton-John 1977Oswalt, Gates & Holmstrom 1977;Travis, Todres & Shannon 1977), occumng in patients requiring intubation for treatment of croup and epiglottitis. Several subsequent reports also described concurrent complications including an approximate 2&25% occurrence rate of pneumothoraces (Kanter & Watchko 1984;Tami et al 1986). Rarer serious sequelae have been described (Musewe, Frewen & Cunningham 1986;Younkers, Meadors & Coveler 1989).…”

Urinary arginine-vasopressin (AVP) excretion in cystic fibrosis (CF)

“…This may be the reason for cases of water intoxication in such patients (Kanter & Watchko 1984). This may be the reason for cases of water intoxication in such patients (Kanter & Watchko 1984).…”