DOI: 10.1016/j.jval.2012.08.1460 View full text |Buy / Rent full text

Abstract: OBJECTIVES: Kaplan-Meier (KM) curves are commonly used to report time-toevent outcomes like overall survival (OS) and progression-free survival. For studies not explicitly reporting hazard ratio (HR) and confidence intervals (CI), KM curves can be utilised to estimate these summary statistics for conducting a meta-analysis. Here, we validate the method proposed by Parmar and colleagues for estimating HR (95%CI) by reading the KM curves. METHODS: Ten randomised controlled trials reporting HR (95%CI) and the as… Show more

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