“…It is not yet known how the thyroid dysfunction in the parents can affect the offsprings. The effect of thyroidal hyperfunction in pregnant mothers is attributed by many authors to be the fetal environmental anomaly acting through the placenta,', 51,56,67,82,89,109,121,133) and the effect is said to persist rather long afte birth.") On the other hand, Prof. Okamoto",",") and his co-workers have observed that the pancreatic Largerhans' islets are under developed in offsprings born from animals with experimental diabetes ; and Taguchi,1") upon study of rats with alloxan induced diabetes, claims that the diabetic condition influences the male and the female first in the early stage of the first reduction-division cycle, and secondly in the middle stage of differentiation of sperms from spermatocytes and in the course of first reduction-division cycle of oocytes, causing stunted development of Langerhan's islets in the offsprings.…”