Psychosocial risk factors of myocardial infarction and adverse effects of streptokinase in public sector hospitals

Abstract

Objectives: This study investigated the psychosocial risk factors of myocardial infarction and time related adverse effects of administration of streptokinase on short-term morbidity and mortality in patients with ST-segment-elevation myocardial infarction (STEMI). Methods: One hundred patients with STEMI treated with streptokinase in the hospital setting were prospectively enrolled in the study. The primary outcome parameter was the incidence of major adverse cardiac events. During hospital stay the psychosocial and demographic risk factors were also investigated. Results: The overall mortality rate was similar in both groups and it was not significant. (5.7% vs 14.5%; P = 0.18). The number of recurrent chest pain was significantly higher in the group 2 compared to the group 1 (25% vs 62.5%; P = .01). The number of hypotesion was significantly higher in the group 1 as compared to the group 2 (30.7% vs 6.2%; P = .009). The demographic and psychosocial risk factors were recorded. Conclusions:The early intravenous administration of streptokinase in the hospital setting leads to a reduced rate of major cardiovascular events compared to delayed administration beyond 2 hours. However, mortality rates were not significantly affected. Secondary prevention should be targeted on modifiable demographic, dietary, and psychosocial risk factors of STEMI.

Vapour pressure and enthalpy of vaporization of aliphatic poly-amines

“…Determinations of the vapour pressures and enthalpies of vaporization of other cyclic amines were conducted by a number of groups in recent years [13][14][15][16][17][18][19][20][21][22][23]. Compilation of the available data is given in table 2.…”

The surface film pressure computations from the adsorption data of organic vapours on carbon black

“…: [1] Hence dc = @ + dT [2] Each term in the above equation defines a well known thermodynamic quantity, namely:…”

“…In previous papers (1,2), a volumetric method for the determination of adsorption isotherms of various organic vapours on carbon black has been described. Adsorption data on methyl acetate, methyl formate, acetaldehyde, methanol, methyl cyanide and methyl ethyl ketone has been reported.…”

Streptokinase and streptokinase card: questionnaire validation to evaluate knowledge among post‐STEMI patients in a Malaysian Tertiary Hospital

“…2 In Malaysia, fibrinolytic therapy is more readily available and constitutes the main reperfusion strategy in the early management of acute STEMI. 3 Fibrinolytic therapy has been shown to reduce mortality when given within the appropriate time frame. [2][3][4] Streptokinase, a non-fibrin-specific fibrinolytic agent, is the most widely used reperfusion therapy in Malaysian public hospitals for STEMI patients.…”

“…3 Fibrinolytic therapy has been shown to reduce mortality when given within the appropriate time frame. [2][3][4] Streptokinase, a non-fibrin-specific fibrinolytic agent, is the most widely used reperfusion therapy in Malaysian public hospitals for STEMI patients. 1 Although tissue plasminogen activator (t-PA) agents, such as tenecteplase have become the first-line thrombolytic agents in various guidelines, streptokinase remains in use in more than 50% of countries worldwide due to its affordability, especially in developing countries.…”