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Cited by 35 publications
(31 citation statements)
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“…The respiratory subtype of panic has a specific profile of pharmacological sensitivity, it is associated with familial risk of PD, and it may predict a greater severity of illness (Briggs et al (1993); Nardi et al, 2003Nardi et al, , 2006aBiber and Alkin, 1999;Onur et al, 2006). Epidemiological studies indicate that the presence of respiratory disorders, such as COPD (Goodwin and Pine, 2002), increases the likelihood of developing PD.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The respiratory subtype of panic has a specific profile of pharmacological sensitivity, it is associated with familial risk of PD, and it may predict a greater severity of illness (Briggs et al (1993); Nardi et al, 2003Nardi et al, , 2006aBiber and Alkin, 1999;Onur et al, 2006). Epidemiological studies indicate that the presence of respiratory disorders, such as COPD (Goodwin and Pine, 2002), increases the likelihood of developing PD.…”
Section: Discussionmentioning
confidence: 99%
“…Briggs et al (1993) demonstrated that patients with the respiratory subtype of panic suffer more spontaneous PAs than patients with the residual subtype and that they respond better to imipramine than to alprazolam. The respiratory subtype has been shown to be associated with increased familial risk of PD (Horwath et al, 1997;Nardi et al, 2003Nardi et al, , 2006a, to be more common among heavy smokers, to have a longer duration and major severity of illness (Biber and Alkin, 1999), and to have a lower resting end-tidal pCO 2 (Moynihan and Gevirtz, 2001) and a higher sensitivity to CO 2 inhalation (Biber and Alkin, 1999;Valenca et al, 2002;Abrams et al, 2006;Nardi et al, 2006a, b). Other clinical features displayed by PD patients with the respiratory subtype include a later onset of the disease and a faster response to nortriptyline (Nardi et al, 2003(Nardi et al, , 2006a, more past traumatic suffocation experiences and respiratory diseases (Bouwer and Stein, 1997;Verburg et al, 1995), higher levels of anxiety sensitivity, and more panic-agoraphobic spectrum symptoms (Onur et al, 2006).…”
Section: Introductionmentioning
confidence: 99%
“…Physiological challenge studies such as those involving CO 2 inhalation, hyperventilation, and breath-holding support these findings and may provide a more objective measure of panic attack symptomatology than self report. In three recent studies, [8][9][10] patients diagnosed with panic disorder were classified into respiratory and nonrespiratory subtype groups and subsequently administered 35 or 65% CO 2 /O 2 admixtures. In each of the studies, a significantly greater proportion of participants in the respiratory subtype group experienced a self-reported panic attack following CO 2 inhalation (63.3-93.7%) than did participants in the nonrespiratory subtype group (33.3-43.4%).…”
Section: Respiratory Subtypementioning
confidence: 99%
“…Instead of questioning the efficacy of the CO 2 challenge to arouse PA in PD patients, this study corroborated the existence of the nR-PD subtype. The second is the experiment conducted by Nardi et al, 34 which compared responsiveness to the 35% CO 2 challenge between 117 PD patients (51 [43.60%] diagnosed with nR-PD and 66 [56.4%] with R-PD), with conclusive findings: R-PDs had a higher incidence of familial history of PD, a higher incidence of previous alcohol abuse, and a lower age of onset.…”
Section: From 2000 To 2012mentioning
confidence: 99%
“…Sixteen articles from this period were analyzed, six of which discussed the different response to the CO 2 challenge between the PD subtypes (R-PD vs. nR-PD): Nardi et al [32][33][34][35][36] and Papp et al 37 These articles were unanimous in observing that, although some PD patients may experience hypercapnia-triggered PAs, those patients who show this hypercapnia might form a consistent group with similar background, manifestations, and prognosis.…”
Section: From 2000 To 2012mentioning
confidence: 99%