Psychological Status and Quality of Life in relation to the Metabolic Syndrome: Isfahan Cohort Study

Abstract

Objective. Current study was designed to investigate the association of metabolic syndrome (MetS) with depression, anxiety, psychological distress, and quality of life (QoL). Design. Two hundred and fifteen contributors with MetS and 253 participants without MetS were randomly selected from 2151 participants of Isfahan Cohort Study who were residents of Isfahan city. Measurements consisted of fasting blood samples, anthropometrics, and self-reported data of 12-item General Health Questionnaire, Hospital Anxiety and Depression Scale, and European Quality of Life-5 Dimension. Binary logistic regression analysis was used to find the association between MetS and four psychological factors. Results. Participants mean age was 56.3 ± 9.8 years. Male/female ratio was 0.86 (217/251). Mean score of depression (P = 0.003), anxiety (P = 0.018), distress (P = 0.047), and QoL (P ≤ 0.001) was significantly higher in MetS group. There were significant increasing relationships between depression (OR 1.10, 95% CI 1.03–1.22), anxiety (OR 1.03, 95% CI 1.05–1.11), and QoL (OR 1.13, 95% CI 1.05–1.23) and MetS when associations were adjusted for other risk factors, but it was not the case for distress (OR 1.03, 95% CI 0.99–1.08). Conclusion. It might be better to consider MetS as a combination of biological and psychological risk factors. Thus, a person with metabolic disease should be recognized as a patient with these factors and be screened for all of them.

Health-related quality of life and metabolic risk in patients with psychosis

“…Previous research shows an association between prevalence of different risk factors for metabolic syndrome and lower HRQoL in patients with depression and anxiety (Roohafza et al, 2012). Both men and women with metabolic syndrome had lower HRQoL compared with controls without the metabolic syndrome in a non-disease specific population study (Frisman and Kristenson, 2009).…”

Components of the metabolic syndrome and depressive symptoms in community-dwelling older people: the Bambuí Cohort Aging Study

“…Different studies have reported a positive trend toward the association between the number of MetS components and depression in young and older adults. 5,10,[13][14][15] However, a significant association between MetS components and depressive symptoms has not been detected. 6,9 To the best of our knowledge, there have been no studies focusing on the moderating effect of increasing number of MetS components on the association between MetS and depressive symptoms in population-based studies including older adults.…”

Common People : Physical health, lifestyle and quality of life in persons with psychosis and their striving to be like everybody else

“…Chou et al (2014) found that psychosocial factors, such as self-efficacy, self-esteem, and social stigma were determinants of lower HRQoL in patients with schizophrenia. Research has also demonstrated a link between the presence of various risk factors for metabolic syndrome and lower HRQoL (Roohafza et al 2012). Other contributing factors that can be linked to lower HRQoL are side effects of second generation antipsychotics (Bebbington et al 2009), social isolation (Sibitz et al 2010), and a high BMI and waist circumference (Faulkner et al 2007).…”