Psychological interventions for non-ulcer dyspepsia

Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies

“…In this study, on the other hand, no significant favourable effect was observed in tandospirone‐treated FD patients. Although we observed slight improvements in 33.3% of tandospirone‐treated patients, other reports demonstrate that even placebo has a favourable effect on symptoms as well 17, 18 . Regarding antidepressants, tricyclic are effective in treating patients with functional gastrointestinal disorders, including FD, 7 and the mechanism behind this positive effect of tricyclic antidepressants has been proposed to be due to an effect on gastric sensitivity.…”

Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies

“…In this study, on the other hand, no significant favourable effect was observed in tandospirone‐treated FD patients. Although we observed slight improvements in 33.3% of tandospirone‐treated patients, other reports demonstrate that even placebo has a favourable effect on symptoms as well 17, 18 . Regarding antidepressants, tricyclic are effective in treating patients with functional gastrointestinal disorders, including FD, 7 and the mechanism behind this positive effect of tricyclic antidepressants has been proposed to be due to an effect on gastric sensitivity.…”

A randomized controlled trial of a 10week group psychotherapeutic treatment added to standard medical treatment in patients with functional dyspepsia

“…Group therapy is more efficient from the health care perspective than individual therapy, but also has a higher dropout rate [5,7]. The dropout rate in our study (20%), composed by a majority of group sessions, was similar to that of Hamilton [4] (19%), that used individual sessions, and much lower than that of Bates et al [21] (48%), that used group therapy.…”

“…However, there are only a limited number of trials evaluating psychological interventions for FD [5,7]. Reviews by Soo et al [5,9] identified only four trials of psychological intervention for FD. Each used different psychological interventions.…”

“…Key criticisms of these studies were [5,9] a) small sample sizes; b) use of statistical techniques that adjusted for baseline differences between groups, which should not be necessary in adequately powered RCT; and c) emphasis on statistical significance rather than clinical significance. In addition, Soo et al [5,9] presented a quantitative description only for the Hamilton study, because the results of the other three trials were presented in a way that did not allow synthesis of the data.…”

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

“…Soo et al, 2004; Thomas, Thomas, Hillier, Galvin, & Baker, 2006; Baker, Brooks, Goodfellow, Bodde, & Aldenkamp, 2007; Ismail, Winkley, & Rabe-Hesketh, 2004). However, cancer was studied more rigorously and with more robust methodological attention, indicating small to medium effect sizes of individual CBT as compared to patient education only in gynecological and head/neck cancers (Zimmerman & Heinrichs, 2006; Luckett, Britton, Clover, & Rankin, 2011), on secondary outcomes such as quality of life, psychological distress (i.e., depression and anxiety), and pain.…”

Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies

“…In this study, on the other hand, no significant favourable effect was observed in tandospirone‐treated FD patients. Although we observed slight improvements in 33.3% of tandospirone‐treated patients, other reports demonstrate that even placebo has a favourable effect on symptoms as well 17, 18 . Regarding antidepressants, tricyclic are effective in treating patients with functional gastrointestinal disorders, including FD, 7 and the mechanism behind this positive effect of tricyclic antidepressants has been proposed to be due to an effect on gastric sensitivity.…”

A randomized controlled trial of a 10week group psychotherapeutic treatment added to standard medical treatment in patients with functional dyspepsia

“…Group therapy is more efficient from the health care perspective than individual therapy, but also has a higher dropout rate [5,7]. The dropout rate in our study (20%), composed by a majority of group sessions, was similar to that of Hamilton [4] (19%), that used individual sessions, and much lower than that of Bates et al [21] (48%), that used group therapy.…”

“…However, there are only a limited number of trials evaluating psychological interventions for FD [5,7]. Reviews by Soo et al [5,9] identified only four trials of psychological intervention for FD. Each used different psychological interventions.…”

“…Key criticisms of these studies were [5,9] a) small sample sizes; b) use of statistical techniques that adjusted for baseline differences between groups, which should not be necessary in adequately powered RCT; and c) emphasis on statistical significance rather than clinical significance. In addition, Soo et al [5,9] presented a quantitative description only for the Hamilton study, because the results of the other three trials were presented in a way that did not allow synthesis of the data.…”

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

“…Soo et al, 2004; Thomas, Thomas, Hillier, Galvin, & Baker, 2006; Baker, Brooks, Goodfellow, Bodde, & Aldenkamp, 2007; Ismail, Winkley, & Rabe-Hesketh, 2004). However, cancer was studied more rigorously and with more robust methodological attention, indicating small to medium effect sizes of individual CBT as compared to patient education only in gynecological and head/neck cancers (Zimmerman & Heinrichs, 2006; Luckett, Britton, Clover, & Rankin, 2011), on secondary outcomes such as quality of life, psychological distress (i.e., depression and anxiety), and pain.…”

Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies

“…In this study, on the other hand, no significant favourable effect was observed in tandospirone‐treated FD patients. Although we observed slight improvements in 33.3% of tandospirone‐treated patients, other reports demonstrate that even placebo has a favourable effect on symptoms as well 17, 18 . Regarding antidepressants, tricyclic are effective in treating patients with functional gastrointestinal disorders, including FD, 7 and the mechanism behind this positive effect of tricyclic antidepressants has been proposed to be due to an effect on gastric sensitivity.…”

A randomized controlled trial of a 10week group psychotherapeutic treatment added to standard medical treatment in patients with functional dyspepsia

“…Group therapy is more efficient from the health care perspective than individual therapy, but also has a higher dropout rate [5,7]. The dropout rate in our study (20%), composed by a majority of group sessions, was similar to that of Hamilton [4] (19%), that used individual sessions, and much lower than that of Bates et al [21] (48%), that used group therapy.…”

“…However, there are only a limited number of trials evaluating psychological interventions for FD [5,7]. Reviews by Soo et al [5,9] identified only four trials of psychological intervention for FD. Each used different psychological interventions.…”

“…Key criticisms of these studies were [5,9] a) small sample sizes; b) use of statistical techniques that adjusted for baseline differences between groups, which should not be necessary in adequately powered RCT; and c) emphasis on statistical significance rather than clinical significance. In addition, Soo et al [5,9] presented a quantitative description only for the Hamilton study, because the results of the other three trials were presented in a way that did not allow synthesis of the data.…”

The Efficacy of Cognitive Behavioral Therapy: A Review of Meta-analyses

“…Soo et al, 2004; Thomas, Thomas, Hillier, Galvin, & Baker, 2006; Baker, Brooks, Goodfellow, Bodde, & Aldenkamp, 2007; Ismail, Winkley, & Rabe-Hesketh, 2004). However, cancer was studied more rigorously and with more robust methodological attention, indicating small to medium effect sizes of individual CBT as compared to patient education only in gynecological and head/neck cancers (Zimmerman & Heinrichs, 2006; Luckett, Britton, Clover, & Rankin, 2011), on secondary outcomes such as quality of life, psychological distress (i.e., depression and anxiety), and pain.…”